Biology:SEPT3
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 Generic protein structure example |
Neuronal-specific septin-3 is a protein that in humans is encoded by the SEPT3 gene.[1]
Function
This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in multiple transcript variants.[1]
References
Further reading
- "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research 6 (9): 791–806. September 1996. doi:10.1101/gr.6.9.791. PMID 8889548.
- "DNA cloning using in vitro site-specific recombination". Genome Research 10 (11): 1788–95. November 2000. doi:10.1101/gr.143000. PMID 11076863.
- "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research 11 (3): 422–35. March 2001. doi:10.1101/gr.GR1547R. PMID 11230166.
- "Human septin 3 on chromosome 22q13.2 is upregulated by neuronal differentiation". Biochemical and Biophysical Research Communications 283 (1): 48–56. April 2001. doi:10.1006/bbrc.2001.4741. PMID 11322766.
- "Phosphorylation of septin 3 on Ser-91 by cGMP-dependent protein kinase-I in nerve terminals". The Biochemical Journal 381 (Pt 3): 753–60. August 2004. doi:10.1042/BJ20040455. PMID 15107017.
- "A genome annotation-driven approach to cloning the human ORFeome". Genome Biology 5 (10): R84. 2005. doi:10.1186/gb-2004-5-10-r84. PMID 15461802.
- "Septin 3 (G-septin) is a developmentally regulated phosphoprotein enriched in presynaptic nerve terminals". Journal of Neurochemistry 91 (3): 579–90. November 2004. doi:10.1111/j.1471-4159.2004.02755.x. PMID 15485489.
- "From ORFeome to biology: a functional genomics pipeline". Genome Research 14 (10B): 2136–44. October 2004. doi:10.1101/gr.2576704. PMID 15489336.
- "The LIFEdb database in 2006". Nucleic Acids Research 34 (Database issue): D415-8. January 2006. doi:10.1093/nar/gkj139. PMID 16381901.
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