Biology:TRIM9

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Tripartite motif-containing protein 9 is a protein that in humans is encoded by the TRIM9 gene.[1][2][3]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms.[3]

Interactions

TRIM9 has been shown to interact with SNAP-25.[2]

References

  1. "The tripartite motif family identifies cell compartments". EMBO J 20 (9): 2140–51. May 2001. doi:10.1093/emboj/20.9.2140. PMID 11331580. 
  2. 2.0 2.1 "Spring, a novel RING finger protein that regulates synaptic vesicle exocytosis". J Biol Chem 276 (44): 40824–33. Oct 2001. doi:10.1074/jbc.M106141200. PMID 11524423. 
  3. 3.0 3.1 "Entrez Gene: TRIM9 tripartite motif-containing 9". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=114088. 

Further reading