Biology:PLXNB2
From HandWiki
 Generic protein structure example |
Plexin-B2 is a protein that in humans is encoded by the PLXNB2 gene.[1][2][3]
Function
Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. (2002)).[supplied by OMIM][3]
Interactions
PLXNB2 has been shown to interact with ARHGEF11.[2][4]
References
- ↑ "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates". Cell 99 (1): 71–80. Oct 1999. doi:10.1016/S0092-8674(00)80063-X. PMID 10520995.
- ↑ 2.0 2.1 "Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF". J Biol Chem 277 (45): 43115–20. Nov 2002. doi:10.1074/jbc.M206005200. PMID 12183458.
- ↑ 3.0 3.1 "Entrez Gene: PLXNB2 plexin B2". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23654.
- ↑ "Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology". Neuron 35 (1): 51–63. Jul 2002. doi:10.1016/S0896-6273(02)00750-X. PMID 12123608.
Further reading
- "Identification and partial sequence of a cDNA that is differentially expressed in human brain tumors". Cancer Lett. 89 (2): 215–21. 1995. doi:10.1016/0304-3835(95)03690-X. PMID 7889532.
- "An expression-independent catalog of genes from human chromosome 22". Genome Res. 5 (3): 214–24. 1996. doi:10.1101/gr.5.3.214. PMID 8593609.
- "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 4 (2): 141–50. 1997. doi:10.1093/dnares/4.2.141. PMID 9205841.
- "The DNA sequence of human chromosome 22". Nature 402 (6761): 489–95. 1999. doi:10.1038/990031. PMID 10591208. Bibcode: 1999Natur.402..489D.
- "Functional regulation of semaphorin receptors by proprotein convertases". J. Biol. Chem. 278 (12): 10094–101. 2003. doi:10.1074/jbc.M210156200. PMID 12533544.
- "Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells". J. Biol. Chem. 278 (28): 25671–7. 2003. doi:10.1074/jbc.M303047200. PMID 12730235.
- "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. 2005. doi:10.1038/nbt971. PMID 15146197.
- "Interplay between scatter factor receptors and B plexins controls invasive growth". Oncogene 23 (30): 5131–7. 2004. doi:10.1038/sj.onc.1207650. PMID 15184888.
- "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. 2007. doi:10.1093/dnares/12.2.117. PMID 16303743.
 |
