Engineering:Tooth regeneration
From HandWiki
Tooth regeneration is a stem cell based regenerative medicine procedure in the field of tissue engineering and stem cell biology to replace damaged or lost teeth by regrowing them from autologous stem cells.[1]
As a source of the new bioengineered teeth, somatic stem cells are collected and reprogrammed to induced pluripotent stem cells which can be placed in the dental lamina directly or placed in a reabsorbable biopolymer[2] in the shape of the new tooth.[3]
History
Young et al.[4] first demonstrated in 2002 that teeth could be regenerated from cells.
See also
- Epithelial cell rests of Malassez
- Polyphyodont
- Regenerative endodontics
- Socket preservation
- Tooth development
References
- ↑ Keishi Otsu; Mika Kumakami-Sakano; Naoki Fujiwara; Kazuko Kikuchi; Laetitia Keller; Hervé Lesot; Hidemitsu Harada (February 4, 2014). "Stem cell sources for tooth regeneration: current status and future prospects". Frontiers in Physiology 5: 36. doi:10.3389/fphys.2014.00036. PMID 24550845.
- ↑ Biopolymer methods in tissue engineering
- ↑ Hill, David J. (2012-05-10). "Toothless no more – Researchers using stem cells to grow new teeth". Singularity Hub. http://singularityhub.com/2012/05/10/toothless-no-more-researchers-using-stem-cells-to-grow-new-teeth/.
- ↑ "Tissue engineering of complex tooth structures on biodegradable polymer scaffolds.". J Dent Res 81 (10): 695–700. 2002. doi:10.1177/154405910208101008. PMID 12351668. https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12351668.
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