Medicine:TAN syndrome

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TAN syndrome
SpecialtyDermatology

Tegumental angiomyxoma-neurothekeoma (TAN syndrome)[1] is a syndrome, an acronym, and eponym[citation needed] proposed by Malaysian ophthalmologist of Chinese Descent, Tan Aik Kah (b. June 1975).[1] Angiomyxomas are associated with LAMB (lentigines, atrial myxomas, muco-cutaneous myxomas, and blue naevi) syndrome,[2] NAME (nevi, atrial myxoma, myxoid neurofibromas, and ephelides)[3] syndrome and Carney syndrome (atrial, cutaneous and mammary myxomas, lentigines, blue naevi, endocrine disorders and testicular tumours).[4]

TAN syndrome is characterized by multiple superficial angiomyxoma and neurothekeoma confined only to the skin (tegument).[1] TAN syndrome may be used to describe myxomas confined to the skin without visceral involvement.[citation needed]

Case

Tan et al. reported a 10-year-old girl with multiple superficial angiomyxoma associated with neurothekeoma palpebrae.[1] There was no evidence of visceral involvement. The lesions were excised with no recurrence during follow up.[1]

References

  1. 1.0 1.1 1.2 1.3 1.4 Aik Kah, Tan; Chui Yong, Ku; Annuar, Faridah Hanom (2011). "Neurothekeoma palpebrae in association with multiple superficial angiomyxomas: Tegumental Angiomyxoma- Neurothekeoma syndrome (TAN syndrome)". Clinics and Practice 1 (3): e67. doi:10.4081/cp.2011.e67. PMID 24765328. 
  2. Rhodes, Arthur R.; Silverman, Robert A.; Harrist, Terence J.; Perez-Atayde, Antonio R. (1984). "Mucocutaneous lentigines, cardiomucocutaneous myxomas, and multiple blue nevi: The 'LAMB' syndrome". Journal of the American Academy of Dermatology 10 (1): 72–82. doi:10.1016/S0190-9622(84)80047-X. PMID 6693605. 
  3. Kamath, Sreenivas (2006). "Cardiac Neoplasms". in Griffin, Brian P.; Rimmerman, Curtis M.; Topol, Eric J.. The Cleveland Clinic Cardiology Board Review. Lippincott Williams & Wilkins. pp. 50–6. ISBN 978-0-7817-5942-7. https://books.google.com/books?id=q9WwVCSQmWkC&pg=PA50. 
  4. Carney Complex at eMedicine