Medicine:Adenolipoma

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Short description: Type of lipoma that develops in sweat glands

Template:Infobox Disease

An adenolipoma is a type of lipoma (benign fat tumor) that develops in the eccrine sweat glands. They can occur either in the skin,[1] or in the thyroid. [2]

Signs and symptoms

Adenolipomas are usually asymptomatic, soft nodules that aren't tender, and are slow-growing.[3] In the case of thyroid adenolipomas, breathing restrictions may be present.[4]

Causes

The cause of adenolipomas is unknown. Theories include improper development in the embryo and invasion from connective tissue.[5]

Diagnosis

Adenolipomas are diagnosed by surgical resection and examining the tumor with a microscope.[5] The presence of eccrine sweat glands are used to distinguish the tumor from a common lipoma. Size and the development of the capsule (tissue surrounding the tumor) can also aid in diagnosis. [6]

Treatment

Adenolipomas are benign tumors, meaning they have no potential to become malignant (cancerous). Surgery is curative,[1] however, adenolipomas can reoccur.[4]

History

Adenolipomas are a relatively recent diagnosis, being first described by Hitchcock et al. in 1993 in a case series. Ait-Ourhrouil and Grosshans later made another case series, disagreeing with the given name and proposing the term peri-sudoral lipoma.[1]

References

  1. 1.0 1.1 1.2 Amir, Rawan; Sheikh, Salwa (2018-04-05). "Adenolipoma of the Skin: A Report of 11 Cases" (in en). Case Reports in Dermatology 10 (1): 76–81. doi:10.1159/000488341. ISSN 1662-6567. PMID 29805368. PMC 5968233. https://www.karger.com/Article/FullText/488341. 
  2. Joon, Pawan; Weerakkody, Yuranga (2014-10-09), "Adenolipoma (thyroid gland)" (in en), Radiopaedia.org, doi:10.53347/rid-31440, http://radiopaedia.org/articles/31440, retrieved 2023-02-27 
  3. AbdullGaffar, Badr; Raman, Lakshmiah G.; Prince, Sheela (June 2014). "Dermal Spindle Cell Adenolipoma" (in en-US). The American Journal of Dermatopathology 36 (6): 527–529. doi:10.1097/DAD.0b013e31829871bd. ISSN 0193-1091. PMID 23974223. https://journals.lww.com/amjdermatopathology/Fulltext/2014/06000/Dermal_Spindle_Cell_Adenolipoma.18.aspx. 
  4. 4.0 4.1 Hjorth, L.; Thomsen, L.B.; Nielsen, V.T. (January 1986). "Adenolipoma of the thyroid gland". Histopathology 10 (1): 91–96. doi:10.1111/j.1365-2559.1986.tb02463.x. PMID 3957249. https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2559.1986.tb02463.x. 
  5. 5.0 5.1 "Adenolipoma". https://www.pathologyoutlines.com/topic/thyroidadenolipoma.html. 
  6. Agua, C. Del; Felipo, F. (2004). "Adenolipoma of the skin" (in en). Dermatology Online Journal 10 (2): 9. doi:10.5070/D30fh507g3. PMID 15530299. https://escholarship.org/uc/item/0fh507g3.