Chemistry:Selective PPAR modulator

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A selective PPAR modulator (SPPARM) is a selective receptor modulator of the peroxisome proliferator-activated receptor (PPAR).[1][2][3] Examples include SPPARMs of the PPARγ, BADGE, EPI-001, INT-131, MK-0533, and S26948.

See also

References

  1. ↑ Fruchart, Jean-Charles; Santos, Raul D.; Aguilar-Salinas, Carlos; Aikawa, Masanori; Al Rasadi, Khalid; Amarenco, Pierre; Barter, Philip J.; Ceska, Richard et al. (4 June 2019). "The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential". Cardiovascular Diabetology 18 (1): 71. doi:10.1186/s12933-019-0864-7. ISSN 1475-2840. PMID 31164165. 
  2. ↑ Fruchart, Jean-Charles; Hermans, Michel P.; Fruchart-Najib, Jamila; Kodama, Tatsuhiko (3 January 2021). "Selective Peroxisome Proliferator-Activated Receptor Alpha Modulators (SPPARMα) in the Metabolic Syndrome: Is Pemafibrate Light at the End of the Tunnel?" (in en). Current Atherosclerosis Reports 23 (1): 3. doi:10.1007/s11883-020-00897-x. ISSN 1534-6242. PMID 33392801. 
  3. ↑ Balint, B. L.; Nagy, L. (March 2006). "Selective modulators of PPAR activity as new therapeutic tools in metabolic diseases". Endocrine, Metabolic & Immune Disorders Drug Targets 6 (1): 33–43. doi:10.2174/187153006776056620. ISSN 1871-5303. PMID 16611163. https://pubmed.ncbi.nlm.nih.gov/16611163/. 




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