Biography:Hendrik Dietz

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Short description: German biophysicist
Hendrik Dietz
Born(1977-12-18)18 December 1977
Dresden, Germany
NationalityGerman
Alma materTechnical University Munich
Ludwig Maximilian University of Munich
Paderborn University
Known forDNA Origami
AwardsLeibniz Prize (2015)
Scientific career
FieldsPhysics
InstitutionsTechnical University Munich
Harvard University

Hendrik Dietz (born December 18, 1977, in Dresden Germany ) is a German physicist known for his contributions in the field of DNA origami. He is a full-professor for biophysics at the Technical University of Munich.

Life

Dietz studied physics in Paderborn University, the University of Zaragoza, and at the LMU Munich. He completed his studies with a diploma in 2004. Subsequently, he became a research associate at the Technical University of Munich (TUM). In 2007, he earned his Dr. rer. nat. with research on the mechanical anisotropy of proteins in single-molecule experiments.[1] After that, he spent two years as a postdoc at Harvard University. Since the summer of 2009, he has been a Professor of Biophysics at the TU München.

Research

Dietz’s main research focus is on DNA nanotechnology. He uses DNA origami to design molecular machines that can execute user-defined tasks. Among these devices are force-sensing nano-structures,[2] gigadalton-sized DNA assemblies,[3] dynamically switching devices,[4] molecular motors,[5][6] and virus traps.[7][8]

In the long term, Dietz hopes to make a significant contribution to the creation of molecular machines and systems with practical benefits for everyday life. This includes uses in medicine such as vaccines or drug delivery vehicles and synthetic enzymes for biologically inspired chemistry.[citation needed]

Awards

  • 2010, European Research Council (ERC) Starting Grant
  • 2015, Gottfried Wilhelm Leibniz Prize of the German Research Foundation (DFG)
  • 2016, European Research Council (ERC) Consolidator Grant
  • 2021, European Research Council Advanced Grant[9]

References

  1. ↑ Dietz, Hendrik (2007). Mechanische Anisotropie von Proteinen in Einzelmolekülexperimenten (Thesis). Technische Universität München.
  2. ↑ Funke, Jonas J.; Ketterer, Philip; Lieleg, Corinna; Schunter, Sarah; Korber, Philipp; Dietz, Hendrik (2016-11-04). "Uncovering the forces between nucleosomes using DNA origami" (in en). Science Advances 2 (11): e1600974. doi:10.1126/sciadv.1600974. ISSN 2375-2548. PMID 28138524. 
  3. ↑ Wagenbauer, Klaus F.; Sigl, Christian; Dietz, Hendrik (2017-12-07). "Gigadalton-scale shape-programmable DNA assemblies" (in en). Nature 552 (7683): 78–83. doi:10.1038/nature24651. ISSN 1476-4687. PMID 29219966. https://www.nature.com/articles/nature24651. 
  4. ↑ Gerling, Thomas; Wagenbauer, Klaus F.; Neuner, Andrea M.; Dietz, Hendrik (2015-03-27). "Dynamic DNA devices and assemblies formed by shape-complementary, non–base pairing 3D components" (in en). Science 347 (6229): 1446–1452. doi:10.1126/science.aaa5372. ISSN 0036-8075. PMID 25814577. https://www.science.org/doi/10.1126/science.aaa5372. 
  5. ↑ Pumm, Anna-Katharina; Engelen, Wouter; Kopperger, Enzo; Isensee, Jonas; Vogt, Matthias; Kozina, Viktorija; Kube, Massimo; Honemann, Maximilian N. et al. (2022-07-20). "A DNA origami rotary ratchet motor" (in en). Nature 607 (7919): 492–498. doi:10.1038/s41586-022-04910-y. ISSN 1476-4687. PMID 35859200. 
  6. ↑ Shi, Xin; Pumm, Anna-Katharina; Isensee, Jonas; Zhao, Wenxuan; Verschueren, Daniel; Martin-Gonzalez, Alejandro; Golestanian, Ramin; Dietz, Hendrik et al. (2022-08-04). "Sustained unidirectional rotation of a self-organized DNA rotor on a nanopore" (in en). Nature Physics 18 (9): 1105–1111. doi:10.1038/s41567-022-01683-z. ISSN 1745-2481. https://www.nature.com/articles/s41567-022-01683-z. 
  7. ↑ Sigl, Christian; Willner, Elena M.; Engelen, Wouter; Kretzmann, Jessica A.; Sachenbacher, Ken; Liedl, Anna; Kolbe, Fenna; Wilsch, Florian et al. (2021-06-14). "Programmable icosahedral shell system for virus trapping" (in en). Nature Materials 20 (9): 1281–1289. doi:10.1038/s41563-021-01020-4. ISSN 1476-4660. PMID 34127822. 
  8. ↑ Monferrer, Alba; Kretzmann, Jessica A.; Sigl, Christian; Sapelza, Pia; Liedl, Anna; Wittmann, Barbara; Dietz, Hendrik (2022-12-27). "Broad-Spectrum Virus Trapping with Heparan Sulfate-Modified DNA Origami Shells" (in en). ACS Nano 16 (12): 20002–20009. doi:10.1021/acsnano.1c11328. ISSN 1936-0851. PMID 36323320. 
  9. ↑ "Biography Hendrik Dietz" (in de-DE). http://www.dietzlab.org/people/bio-dietz/. 



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