Biography:Jian Ma (computer scientist)

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Short description: American computer scientist
Jian Ma
马坚
Jian Ma.jpg
CitizenshipUnited States
Awards
  • Guggenheim Fellowship (2020)
  • AAAS Fellow (2022)
Scientific career
Fields
Institutions
Academic advisorsDavid Haussler (postdoc advisor), Webb Miller (PhD advisor)
Websitewww.cs.cmu.edu/~jianma/

Jian Ma (Chinese: 马坚) is an American computer scientist and computational biologist.[1] He is the Ray and Stephanie Lane Professor of Computational Biology in the School of Computer Science at Carnegie Mellon University.[2][3][4] He is a faculty member in the Ray and Stephanie Lane Computational Biology Department. His lab develops machine learning algorithms to study the structure and function of the human genome[5] and cellular organization and their implications for evolution, health and disease. During his Ph.D. and postdoc training, he developed algorithms to reconstruct the ancestral mammalian genome.[6] His research group has recently pioneered a series of new machine learning methods for 3D epigenomics, comparative genomics, spatial genomics, and single-cell analysis. He received an NSF CAREER award in 2011.[7] In 2020, he was awarded a Guggenheim Fellowship[8][9][10] in Computer Science. He is an elected Fellow of the American Association for the Advancement of Science.[11] He leads an NIH 4D Nucleome Center to develop machine learning algorithms to better understand the cell nucleus.[5][12] He is the Program Chair for RECOMB 2024.[13]

Recent Publications

  • Zhang Y, Boninsegna L, Yang M, Misteli T, Alber F, and Ma J. Computational methods for analysing multiscale 3D genome organization. Nature Reviews Genetics, https://doi.org/10.1038/s41576-023-00638-1, 2023.
  • Chidester B, Zhou T, Alam S, and Ma J. SPICEMIX enables integrative single-cell spatial modeling of cell identity. Nature Genetics, 55(1):78-88, 2023. [Cover Article]
  • Zhang R, Zhou T, and Ma J. Ultrafast and interpretable single-cell 3D genome analysis with Fast-Higashi. Cell Systems, 13(10):P798-807.E6, 2022. [Cover Article]
  • Zhu X, Zhang Y, Wang Y, Tian D, Belmont AS, Swedlow JR, and Ma J. Nucleome Browser: An integrative and multimodal data navigation platform for 4D Nucleome. Nature Methods, 19(8):911-913, 2022.
  • Zhang R, Zhou T, and Ma J. Multiscale and integrative single-cell Hi-C analysis with Higashi. Nature Biotechnology, 40:254–261, 2022.
  • Zhang R and Ma J. MATCHA: Probing multi-way chromatin interaction with hypergraph representation learning. Cell Systems, 10(5):397-407.E5, 2020.
  • Tian D, Zhang R, Zhang Y, Zhu X, and Ma J. MOCHI enables discovery of heterogeneous interactome modules in 3D nucleome. Genome Research, 30(2):227-238, 2020. [Cover Article]
  • Yang Y, Zhang Y, Ren B, Dixon J, and Ma J. Comparing 3D genome organization in multiple species using Phylo-HMRF. Cell Systems, 8(6):494-505.e14, 2019.
  • Ma J and Duan Z. Replication timing becomes intertwined with 3D genome organization. Cell, 176(4):681-684, 2019
  • Yang Y, Gu Q, Zhang Y, Sasaki T, Crivello J, O'Neill R, Gilbert DM, and Ma J. Continuous-trait probabilistic model for comparing multi-species functional genomic data. Cell Systems, 7(2):208-218.e11, 2018.

References

  1. "Jian Ma - Google Scholar Citations". https://scholar.google.com/citations?hl=en&user=nDw9v78AAAAJ&view_op=list_works&sortby=pubdate. 
  2. "Jian Ma Webpage at Carnegie Mellon". https://www.cs.cmu.edu/~jianma/. 
  3. Carnegie Mellon. "Jian Ma - Computational Biology Department - School of Computer Science - Carnegie Mellon University" (in en). http://cbd.cmu.edu/people/ma.html. 
  4. "SCS Faculty Receive Endowed Professorships" (in en). https://www.cs.cmu.edu/news/2021/faculty-awards. 
  5. 5.0 5.1 Carnegie Mellon. "Carnegie Mellon Heads New Center for Studying Structure of Cell Nucleus - News - Carnegie Mellon University" (in en). http://www.cmu.edu/news/stories/archives/2020/october/new-center-cell-nucleus.html. 
  6. Pennisi, Elizabeth (2005-06-03). "Extinct Genome Under Construction" (in en). Science 308 (5727): 1401–1402. doi:10.1126/science.308.5727.1401b. ISSN 0036-8075. PMID 15933177. https://www.science.org/doi/10.1126/science.308.5727.1401b. 
  7. "Jian Ma receives CAREER award for large-scale Genomic Studies | Carl R. Woese Institute for Genomic Biology". https://www.igb.illinois.edu/article/jian-ma-receives-career-award-large-scale-genomic-studies. 
  8. "John Simon Guggenheim Foundation | Jian Ma" (in en-US). https://www.gf.org/fellows/all-fellows/jian-ma/. 
  9. "John Simon Guggenheim Foundation | 2020 Guggenheim Fellowship winners announced" (in en-US). https://www.gf.org/news/foundation-news/2020-guggenheim-fellowship-winners-announced/. 
  10. Carnegie Mellon (2020-04-10). "Jian Ma Wins Guggenheim Fellowship - News - Carnegie Mellon University" (in en). http://www.cmu.edu/news/stories/archives/2020/april/jia-ma-awarded-guggenheim-fellowship.html. 
  11. "Jian Ma Elected 2022 AAAS Fellow" (in en). https://www.cs.cmu.edu/news/2023/ma-aaas-fellow. 
  12. "CMU tapped to lead NIH research center building 3D map of cell nuclei" (in en). https://www.post-gazette.com/business/tech-news/2020/10/15/Carnegie-Mellon-University-National-Institutes-of-Health-research-center-structure-cell-nuclei/stories/202010150075. 
  13. "RECOMB 2024 | HOME". https://recomb.org/recomb2024/index.html. 

External links