Biography:Keith E. Mostov

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Short description: American cell biologist

Keith E. Mostov is an American cell biologist. He received a BA from University of Chicago in 1976 and during 1976–77 he was a Rhodes Scholar at New College, Oxford.[1] Mostov received a PhD in Biological Science from the Rockefeller University in the laboratory of Nobel laureate Günter Blobel in 1983, and an MD from Weill Cornell Medicine in 1984. He was a Whitehead Fellow[2] at the Whitehead Institute of MIT from 1984 to 1989. In 1989, Mostov joined the faculty of the University of California, San Francisco, School of Medicine, where he is currently Professor.[3] Mostov and colleagues discovered and sequenced the Polymeric Immunoglobulin Receptor (pIgR) and proposed the generally accepted model of its pathway and function.[4] Neil E. Simister and Mostov cloned and sequenced the Neonatal Fc Receptor (FcRn).[5] Mostov and colleagues showed how signals in the pIgR direct its polarized trafficking and how polarized MDCK epithelial cells form three-dimensional structures with lumens and tubules.[4] Mostov and colleagues further found how simple rules cause different branching patterns in kidney as compared to other branching tubular organs [6]

Honors and awards

  • Rhodes Scholar [1]
  • Searle Scholar[7]
  • Charles E. Culpeper Foundation Medical Scholar[8]
  • Mallinckrodt Foundation Scholar[9]
  • NIH NIAID MERIT Award[3]
  • American Society for Cell Biology ASCB Fellow[10]

References

  1. 1.0 1.1 Burks, Edward C. (1976-09-30). "Rhodes Scholars —From a Playwright to a Soldier— Sail for England" (in en-US). The New York Times. ISSN 0362-4331. https://www.nytimes.com/1976/09/30/archives/new-jersey-pages-rhodes-scholars-from-a-playwright-to-a-soldier.html. 
  2. "Whitehead Institute of MIT" (in EN). https://wi.mit.edu/select-past-fellows. 
  3. 3.0 3.1 "Keith Mostov, MD, PhD" (in en). https://cancer.ucsf.edu/people/mostov.keith. 
  4. 4.0 4.1 Apodaca, Gerard; Gallo, Luciana I.; Bryant, David M. (December 2012). "Role of membrane traffic in the generation of epithelial cell asymmetry" (in en). Nature Cell Biology 14 (12): 1235–1243. doi:10.1038/ncb2635. ISSN 1476-4679. PMID 23196841. 
  5. Parham, Peter (January 1989). "MHC meets mother's milk" (in en). Nature 337 (6203): 118–119. doi:10.1038/337118a0. ISSN 1476-4687. PMID 2911346. Bibcode1989Natur.337..118P. 
  6. Yu, Wei; Marshall, Wallace F.; Metzger, Ross J.; Brakeman, Paul R.; Morsut, Leonardo; Lim, Wendell; Mostov, Keith E. (2019-09-25). "Simple Rules Determine Distinct Patterns of Branching Morphogenesis" (in en). Cell Systems 9 (3): 221–227. doi:10.1016/j.cels.2019.08.001. ISSN 2405-4712. PMID 31557453. 
  7. "Keith E. Mostov" (in en). https://www.searlescholars.net/people/keith-e-mostov. 
  8. "mostov / Collections: Charles E. Culpeper Foundation, Inc. records, 1866-2001 - Blacklight Search Results". https://www.empireadc.org/search/?f%5Bcollection_sim%5D%5B%5D=Charles+E.+Culpeper+Foundation,+Inc.+records,+1866-2001&search_field=all_fields&q=mostov. 
  9. "Keith Mostov, MD, PhD" (in en). https://cancer.ucsf.edu/people/mostov.keith. 
  10. "ASCB Fellows" (in en-US). https://www.ascb.org/grants-awards/fellows/.