Biology:SH3GL1

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Endophilin-A2 is a protein that in humans is encoded by the SH3GL1 gene.

Further reading

• "EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia.". Proc. Natl. Acad. Sci. U.S.A. 94 (6): 2563–8. 1997. doi:10.1073/pnas.94.6.2563. PMID 9122235. Bibcode: 1997PNAS...94.2563S. 
• "The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain.". Proc. Natl. Acad. Sci. U.S.A. 94 (16): 8569–74. 1997. doi:10.1073/pnas.94.16.8569. PMID 9238017. Bibcode: 1997PNAS...94.8569R. 
• "The SH3 domains of endophilin and amphiphysin bind to the proline-rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificity.". J. Biol. Chem. 274 (45): 32001–7. 1999. doi:10.1074/jbc.274.45.32001. PMID 10542231. 
• "The interaction between EEN and Abi-1, two MLL fusion partners, and synaptojanin and dynamin: implications for leukaemogenesis.". Leukemia 14 (4): 594–601. 2000. doi:10.1038/sj.leu.2401692. PMID 10764144. 
• "Expression and protein-binding studies of the EEN gene family, new interacting partners for dynamin, synaptojanin and huntingtin proteins.". Biochem. J. 348 (2): 447–58. 2000. doi:10.1042/0264-6021:3480447. PMID 10816441. 
• "The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met". Nature 416 (6877): 187–90. 2002. doi:10.1038/416187a. PMID 11894096. Bibcode: 2002Natur.416..187P. 
• "Alix (ALG-2-interacting protein X), a protein involved in apoptosis, binds to endophilins and induces cytoplasmic vacuolization". J. Biol. Chem. 277 (32): 29108–15. 2002. doi:10.1074/jbc.M204019200. PMID 12034747. 
• "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
• "Identification and characterization of EBP, a novel EEN binding protein that inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein". Blood 103 (4): 1445–53. 2004. doi:10.1182/blood-2003-07-2452. PMID 14551139. 
• "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039. 
• "Functional contribution of EEN to leukemogenic transformation by MLL-EEN fusion protein". Oncogene 23 (19): 3385–94. 2004. doi:10.1038/sj.onc.1207402. PMID 15077184. 
• "Subcellular localization of EEN/endophilin A2, a fusion partner gene in leukaemia". Biochem. J. 383 (Pt 1): 27–35. 2005. doi:10.1042/BJ20040041. PMID 15214844. 
• "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334. 
• "Identification of novel CBP interacting proteins in embryonic orofacial tissue". Biochem. Biophys. Res. Commun. 329 (3): 1010–7. 2005. doi:10.1016/j.bbrc.2005.02.075. PMID 15752756. 
• "Activation of EGF receptor endocytosis and ERK1/2 signaling by BPGAP1 requires direct interaction with EEN/endophilin II and a functional RhoGAP domain". J. Cell Sci. 118 (Pt 12): 2707–21. 2005. doi:10.1242/jcs.02383. PMID 15944398. 
• "Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways". Hum. Mol. Genet. 14 (19): 2893–909. 2005. doi:10.1093/hmg/ddi321. PMID 16115810. 
• "A human protein-protein interaction network: a resource for annotating the proteome". Cell 122 (6): 957–68. 2005. doi:10.1016/j.cell.2005.08.029. PMID 16169070. 
• "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.