Biology:KIRREL2
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
Generic protein structure example |
Kin of IRRE-like protein 2, also known as NEPH3, is a protein that in humans is encoded by the KIRREL2 gene.[1][2][3] It is primarily expressed in β cells of the pancreatic islets.[1]
KIRREL2 is a member of the NEPH protein family, which includes NEPH1 (KIRREL) and NEPH2 (KIRREL3). NEPH proteins bind the
References
- ↑ 1.0 1.1 "Kirrel2, a novel immunoglobulin superfamily gene expressed primarily in beta cells of the pancreatic islets". Genomics 82 (2): 130–42. Jul 2003. doi:10.1016/S0888-7543(03)00110-1. PMID 12837264.
- ↑ "Filtrin is a novel member of nephrin-like proteins". Biochem Biophys Res Commun 300 (2): 364–70. Dec 2002. doi:10.1016/S0006-291X(02)02854-1. PMID 12504092.
- ↑ "Entrez Gene: KIRREL2 kin of IRRE like 2 (Drosophila)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84063.
Further reading
- "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. 1997. doi:10.1101/gr.6.9.791. PMID 8889548.
- "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. 2001. doi:10.1101/gr.GR1547R. PMID 11230166.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. 2003. doi:10.1101/gr.1293003. PMID 12975309.
- "Signal peptide prediction based on analysis of experimentally verified cleavage sites.". Protein Sci. 13 (10): 2819–24. 2005. doi:10.1110/ps.04682504. PMID 15340161.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Densin and filtrin in the pancreas and in the kidney, targets for humoral autoimmunity in patients with type 1 diabetes.". Diabetes Metab. Res. Rev. 23 (2): 119–26. 2007. doi:10.1002/dmrr.655. PMID 16741999.