Biology:Intramyocellular lipids
From HandWiki
Intramyocellular lipids (or IMCL) are fats stored in droplets in muscle cells. They provide an important energy source for working muscle. During exercise, a large amount of circulating free fatty acids are directed into muscle cells for energy; during rest, incoming fatty acids are instead stored in the muscle cell as triglycerides for later burning.[1] However, an increase in muscle insulin resistance, caused by obesity, diabetes mellitus type 2, and metabolic syndrome, will result in an excess accumulation of intramyocellular lipids.[2][3]
See also
References
- ↑ "Intramyocellular lipid content is increased after exercise in nonexercising human skeletal muscle". Journal of Applied Physiology 95 (6): 2328–2332. December 1, 2003. doi:10.1152/japplphysiol.00304.2003. PMID 12923116. https://cris.maastrichtuniversity.nl/portal/en/publications/intramyocellular-lipid-content-is-increased-after-exercise-in-nonexercising-human-skeletal-muscle(eb791615-097a-47ca-a6eb-878d2336e460).html.
- ↑ "Intramyocellular lipid kinetics and insulin resistance". Lipids Health Dis 6: 18. 2007. doi:10.1186/1476-511X-6-18. PMID 17650308.
- ↑ "Insulin resistance in morbid obesity: reversal with intramyocellular fat depletion". Diabetes 51 (1): 144–51. 2002. doi:10.2337/diabetes.51.1.144. PMID 11756334.
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