Biology:CRIP2
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Cysteine-rich protein 2 is a protein that in humans is encoded by the CRIP2 gene.[1][2][3][4]
CRIP2 and the closely related CRIP1 are cysteine-rich proteins containing two LIM domains. They are highly expressed during cardiovascular development and act to bridge serum response factor and GATA proteins and stimulate smooth muscle target genes.[5]
References
- ↑ "A novel cDNA encoding for a LIM domain protein located at human chromosome 14q32 as a candidate for leukemic translocation". Biochem Mol Biol Int 39 (4): 747–54. Feb 1997. doi:10.1080/15216549600201831. PMID 8843343.
- ↑ "Human ESP1/CRP2, a member of the LIM domain protein family: characterization of the cDNA and assignment of the gene locus to chromosome 14q32.3". Genomics 31 (2): 167–76. January 1996. doi:10.1006/geno.1996.0028. PMID 8824798.
- ↑ "Cysteine-rich protein 2, a novel substrate for cGMP kinase I in enteric neurons and intestinal smooth muscle". J Biol Chem 275 (8): 5504–11. Mar 2000. doi:10.1074/jbc.275.8.5504. PMID 10681529.
- ↑ "Entrez Gene: CRIP2 cysteine-rich protein 2". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1397.
- ↑ "Cysteine-rich LIM-only proteins CRP1 and CRP2 are potent smooth muscle differentiation cofactors". Dev. Cell 4 (1): 107–18. January 2003. doi:10.1016/S1534-5807(02)00396-9. PMID 12530967.
External links
- Human CRIP2 genome location and CRIP2 gene details page in the UCSC Genome Browser.
Further reading
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y; Yoshitomo-Nakagawa K; Maruyama K et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- van Ham M; Croes H; Schepens J et al. (2004). "Cloning and characterization of mCRIP2, a mouse LIM-only protein that interacts with PDZ domain IV of PTP-BL". Genes Cells 8 (7): 631–44. doi:10.1046/j.1365-2443.2003.00660.x. PMID 12839623.
- Ota T; Suzuki Y; Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Lim J; Hao T; Shaw C et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
PDB gallery | |
|---|---|
|
 |
