Biology:Zinc finger protein 334

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Short description: Protein found in humans


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example


Zinc finger protein 334 is a protein that in humans is encoded by the ZNF334 gene. [1]

Function

This gene encodes a member of the C2H2 zinc finger family. The encoded protein contains a Krueppel-associated box, fourteen C2H2 zinc finger domains, and four C2H2-type/integrase DNA-binding domains. Decreased expression of this gene may be a marker for rheumatoid arthritis. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

References

Further reading

  • "The in vitro modulatory effect of TNFα on the mRNA expression and protein levels of zinc finger protein ZNF334 in CD4(+) lymphocytes of healthy people". Acta Biochim. Pol. 62 (1): 113–7. 2015. doi:10.18388/abp.2014_857. PMID 25738173. 

This article incorporates text from the United States National Library of Medicine, which is in the public domain.