Biology:CEP55
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
![]() Generic protein structure example |
Centrosomal protein of 55 kDa (Cep55), is a protein that in humans is encoded by the CEP55 gene.[1][2]
Cep55 is a mitotic phosphoprotein that plays a key role in cytokinesis, the final stage of cell division.[3] and cilia formation in neural stem cells.[4]
References
- ↑ "Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis". Dev Cell 9 (4): 477–88. Oct 2005. doi:10.1016/j.devcel.2005.09.003. PMID 16198290.
- ↑ "Entrez Gene: CEP55 centrosomal protein 55kDa". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55165.
- ↑ "Cep55 stabilization is required for normal execution of cytokinesis". Cell Cycle 8 (22): 3742–3749. November 2009. doi:10.4161/cc.8.22.10047. PMID 19855176.
- ↑ Behnam Rashidieh; Belal Shohayeb; Amanda Louise Bain; Patrick R. J. Fortuna; Debottam Sinha; Andrew Burgess; Richard Mills; Rachael C. Adams et al. (October 2021). "Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis". PLOS Genetics 17 (10): e1009334. doi:10.1371/journal.pgen.1009334. PMID 34710087.
External links
- Human CEP55 genome location and CEP55 gene details page in the UCSC Genome Browser.
Further reading
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "The DNA sequence and comparative analysis of human chromosome 10". Nature 429 (6990): 375–81. 2004. doi:10.1038/nature02462. PMID 15164054. Bibcode: 2004Natur.429..375D.
- "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- "The novel centrosomal associated protein CEP55 is present in the spindle midzone and the midbody". Genomics 87 (2): 243–53. 2006. doi:10.1016/j.ygeno.2005.11.006. PMID 16406728.
- "Cep55, a Microtubule-bundling Protein, Associates with Centralspindlin to Control the Midbody Integrity and Cell Abscission during Cytokinesis". Mol. Biol. Cell 17 (9): 3881–96. 2006. doi:10.1091/mbc.E06-01-0015. PMID 16790497.
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. 2006. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- "FLJ10540-elicited cell transformation is through the activation of PI3-kinase/AKT pathway". Oncogene 26 (29): 4272–83. 2007. doi:10.1038/sj.onc.1210207. PMID 17237822.
- "Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery". Science 316 (5833): 1908–12. 2007. doi:10.1126/science.1143422. PMID 17556548. Bibcode: 2007Sci...316.1908C. https://zenodo.org/record/896126.
- "Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis". EMBO J. 26 (19): 4215–27. 2007. doi:10.1038/sj.emboj.7601850. PMID 17853893.
![]() | Original source: https://en.wikipedia.org/wiki/CEP55.
Read more |