Biology:Jpx (gene)
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Short description: Non-coding RNA in the species Homo sapiens
 Generic protein structure example |
In molecular biology, JPX transcript, XIST activator (non-protein coding), also known as Jpx, is a long non-coding RNA. In humans, it is located on the X chromosome. It was identified during sequence analysis of the X inactivation centre, surrounding the Xist gene.[1] Jpx upregulates expression of Xist.[2]
See also
- Long noncoding RNA
References
- ↑ "Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine.". Genome Res 12 (6): 894–908. 2002. doi:10.1101/gr.152902. PMID 12045143.
- ↑ "The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation.". Cell 143 (3): 390–403. 2010. doi:10.1016/j.cell.2010.09.049. PMID 21029862.
Further reading
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. 2002. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Distinct class of putative "non-conserved" promoters in humans: comparative studies of alternative promoters of human and mouse genes.". Genome Res. 17 (7): 1005–1014. 2007. doi:10.1101/gr.6030107. PMID 17567985.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–45. 2004. doi:10.1038/ng1285. PMID 14702039.
- "[Comparative organization and the origin of noncoding regulatory RNA genes from X-chromosome inactivation center of human and mouse].". Genetika 46 (10): 1386–1391. 2010. PMID 21254562.
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