Biology:ArcLight

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Short description: Genetically-encoded voltage indicator

ArcLight is a genetically-encoded voltage indicator (GEVI) created from Ciona intestinalis voltage sensor and the fluorescent protein super ecliptic pHluorin that carries a critical point mutation (A227D).[1]

References

  1. ↑ Jin, Lei; Han, Zhou; Platisa, Jelena; Wooltorton, Julian R.A.; Cohen, Lawrence B.; Pieribone, Vincent A. (2012). "Single Action Potentials and Subthreshold Electrical Events Imaged in Neurons with a Fluorescent Protein Voltage Probe". Neuron 75 (5): 779–785. doi:10.1016/j.neuron.2012.06.040. PMID 22958819. 





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