Biology:rs1800532
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| SNP: rs1800532 | |
|---|---|
| Name(s) | A218C |
| Gene | TPH1 |
| Chromosome | 11 |
| Region | Intron 7 |
| External databases | |
| Ensembl | Human SNPView |
| dbSNP | 1800532 |
| HapMap | 1800532 |
| SNPedia | 1800532 |
In genetics, rs1800532 (A218C) is a genetic variant. It is a single nucleotide polymorphism in the TPH1 gene and located in intron 7.
It has been examined in relation to personality traits.[1][2][3]
A779C is another SNP in same intron.
References
- ↑ Shih-Jen Tsai, Ying-Chieh Wang, Jen-Yeu Chen & Chen-Jee Hong (2003). "Allelic variants of the tryptophan hydroxylase (A218C) and serotonin 1B receptor (A-161T) and personality traits". Neuropsychobiology 48 (2): 68–71. doi:10.1159/000072879. PMID 14504413.
- ↑ Ion Anghelescu, Christoph Klawe, Christoph Fehr, Peter Singer, Alexandra Schleicher, Hubertus Himmerich, Christoph Hiemke, Norbert Dahmen & Armin Szegedi (July 2005). "The TPH intron 7 A218C polymorphism and TCI dimension scores in alcohol-dependent patients: hints to nonspecific psychopathology". Addictive Behaviors 30 (6): 1135–43. doi:10.1016/j.addbeh.2004.11.002. PMID 15925123.
- ↑ Akihito Suzuki, Takashi Fukasawa, Hiroaki Shiraishi, Genki Ishii, Shingo Oshino, Toshiaki Aoshima & Koichi Otani (March 2007). "No association between the TPH A218C polymorphism and personality traits in Japanese healthy subjects". Progress in Neuro-Psychopharmacology & Biological Psychiatry 31 (2): 395–398. doi:10.1016/j.pnpbp.2006.10.003. PMID 17116352.
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