Biology:Suppression of tumorigenicity 2

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Suppression of tumorigenicity 2 [1] is a gene that in humans is located on chromosome 11p14.3-p12. This region (ST2; GeneID: 6761)[2] on chromosome 11 represents a putative locus that is associated with various forms of cancer. It has been confused in the published literature [3] with the IL1RL1 gene (GeneID: 9173),[4] which has the alias ST2, but is located on chromosome 2 and encodes a member of the interleukin 1 receptor family, IL1RL1.

References

  1. ↑ "NCBI gene - ST2". https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=DetailsSearch&Term=6761. 
  2. ↑ "ST2 Gene". GeneCards. https://www.genecards.org/cgi-bin/carddisp.pl?gene=ST2. 
  3. ↑ Griesenauer, Brad; Paczesny, Sophie (24 April 2017). "The ST2/IL-33 Axis in Immune Cells during Inflammatory Diseases". Frontiers in Immunology (Frontiers) 8: 475. doi:10.3389/fimmu.2017.00475. PMID 28484466. 
  4. ↑ "IL1RL1 Gene". Frontiers. https://www.genecards.org/cgi-bin/carddisp.pl?gene=IL1RL1. 



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