Biology:SH2D2A
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SH2 domain-containing protein 2A is a protein that in humans is encoded by the SH2D2A gene.[1][2]
Interactions
SH2D2A has been shown to interact with MAP3K2.[3]
References
- ↑ "Molecular cloning of a T cell-specific adapter protein (TSAd) containing an Src homology (SH) 2 domain and putative SH3 and phosphotyrosine binding sites". The Journal of Biological Chemistry 273 (8): 4539–46. February 1998. doi:10.1074/jbc.273.8.4539. PMID 9468509.
- ↑ "Entrez Gene: SH2D2A SH2 domain protein 2A". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9047.
- ↑ "MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway". The Journal of Biological Chemistry 276 (7): 5093–100. February 2001. doi:10.1074/jbc.M003719200. PMID 11073940.
Further reading
- "The emerging role of the T cell-specific adaptor (TSAd) protein as an autoimmune disease-regulator in mouse and man". Immunology Letters 97 (2): 165–70. March 2005. doi:10.1016/j.imlet.2004.10.019. PMID 15752554.
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. January 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. October 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- "Lad, an adapter protein interacting with the SH2 domain of p56lck, is required for T cell activation". Journal of Immunology 163 (10): 5242–9. November 1999. PMID 10553045.
- "RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation". The Journal of Experimental Medicine 190 (11): 1657–68. December 1999. doi:10.1084/jem.190.11.1657. PMID 10587356.
- "VRAP is an adaptor protein that binds KDR, a receptor for vascular endothelial cell growth factor". The Journal of Biological Chemistry 275 (9): 6059–62. March 2000. doi:10.1074/jbc.275.9.6059. PMID 10692392.
- "The SH2D2A gene encoding the T-cell-specific adapter protein (TSAd) is localized centromeric to the CD1 gene cluster on human Chromosome 1". Immunogenetics 51 (3): 179–85. March 2000. doi:10.1007/s002510050029. PMID 10752626.
- "Genetic association between juvenile rheumatoid arthritis and polymorphism in the SH2D2A gene". Genes and Immunity 5 (4): 310–2. June 2004. doi:10.1038/sj.gene.6364093. PMID 15129233.
- "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nature Biotechnology 23 (1): 94–101. January 2005. doi:10.1038/nbt1046. PMID 15592455.
- "VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis". The EMBO Journal 24 (13): 2342–53. July 2005. doi:10.1038/sj.emboj.7600709. PMID 15962004.
- "The adaptor protein Lad associates with the G protein beta subunit and mediates chemokine-dependent T-cell migration". Blood 109 (12): 5122–8. June 2007. doi:10.1182/blood-2005-10-061838. PMID 17327418.
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