Biology:DEF6

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Differentially expressed in FDCP 6 homolog is a protein that in humans is encoded by the DEF6 gene.[1][2]

References

Further reading

  • "Cooperation of DEF6 with activated Rac in regulating cell morphology". The Journal of Biological Chemistry 282 (3): 2011–8. Jan 2007. doi:10.1074/jbc.M605153200. PMID 17121847. 
  • "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. Oct 2005. doi:10.1038/nature04209. PMID 16189514. 
  • "DEF6, a novel PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA". Experimental Cell Research 294 (2): 335–44. Apr 2004. doi:10.1016/j.yexcr.2003.12.004. PMID 15023524. 
  • "T cell receptor engagement leads to the recruitment of IBP, a novel guanine nucleotide exchange factor, to the immunological synapse". The Journal of Biological Chemistry 278 (44): 43541–9. Oct 2003. doi:10.1074/jbc.M308960200. PMID 12923183. 
  • "Molecular cloning of IBP, a SWAP-70 homologous GEF, which is highly expressed in the immune system". Human Immunology 64 (4): 389–401. Apr 2003. doi:10.1016/S0198-8859(03)00024-7. PMID 12651066. 
  • "SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells". Immunity 18 (3): 403–14. Mar 2003. doi:10.1016/S1074-7613(03)00054-2. PMID 12648457.