Biology:DRD1IP
From HandWiki
Revision as of 09:03, 23 October 2021 by imported>Rtextdoc (over-write)
 Generic protein structure example |
Neuron-specific vesicular protein calcyon is a protein that in humans is encoded by the CALY gene.[1][2] Its alternative name is Calcyon.
Function
The protein encoded by this gene is a type II single transmembrane protein. It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors. The encoded protein interacts with dopamine receptor D1 and may interact with other DA receptor subtypes and/or GPCRs.[2]
References
- ↑ "Calcyon mRNA expression in the frontal-striatal circuitry and its relationship to vesicular processes and ADHD". Behavioral and Brain Functions 3 (1): 33. July 2007. doi:10.1186/1744-9081-3-33. PMID 17623072.
- ↑ 2.0 2.1 "Entrez Gene: DRD1IP dopamine receptor D1 interacting protein". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50632.
Further reading
- "Protein-protein interactions at G-protein-coupled receptors". Trends in Pharmacological Sciences 22 (10): 513–8. October 2001. doi:10.1016/S0165-6147(00)01801-0. PMID 11583808.
- "Elevated intracellular calcium triggers recruitment of the receptor cross-talk accessory protein calcyon to the plasma membrane". The Journal of Biological Chemistry 278 (51): 51654–63. December 2003. doi:10.1074/jbc.M305803200. PMID 14534309.
- "CALCYON gene variation, schizophrenia, and cocaine dependence". American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics 125B (1): 25–30. February 2004. doi:10.1002/ajmg.b.20092. PMID 14755439.
- "Association of the calcyon gene (DRD1IP) with attention deficit/hyperactivity disorder". Molecular Psychiatry 10 (12): 1117–25. December 2005. doi:10.1038/sj.mp.4001737. PMID 16172615.
- "Calcyon, a novel partner of clathrin light chain, stimulates clathrin-mediated endocytosis". The Journal of Biological Chemistry 281 (22): 15182–93. June 2006. doi:10.1074/jbc.M600265200. PMID 16595675.
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. November 2006. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- "Intracellular dynamics of calcyon, a neuron-specific vesicular protein". NeuroReport 18 (15): 1547–51. October 2007. doi:10.1097/WNR.0b013e3282f03f51. PMID 17885599.
 |
