View source for Biology:DTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase

{{Short description|Enzyme}}
{{lowercase title}}
{{Infobox enzyme
| Name       = DTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
| EC_number  = 2.1.1.234
| CAS_number =
| GO_code    = 
| image      = 
| width      = 
| caption    =  
}}
'''DTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase''' ({{EC number|2.1.1.234}}, ''DesVI'') is an [[Biology:Enzyme|enzyme]] with [[Biology:List of enzymes|systematic name]] ''S-adenosyl-L-methionine:dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose 3-N,N-dimethyltransferase''.<ref>{{cite journal | vauthors = Chen H, Yamase H, Murakami K, Chang CW, Zhao L, Zhao Z, Liu HW | title = Expression, purification, and characterization of two N,N-dimethyltransferases, tylM1 and desVI, involved in the biosynthesis of mycaminose and desosamine | journal = Biochemistry | volume = 41 | issue = 29 | pages = 9165–83 | date = July 2002 | pmid = 12119032 | doi = 10.1021/bi020245j }}</ref><ref>{{cite journal | vauthors = Burgie ES, Holden HM | title = Three-dimensional structure of DesVI from Streptomyces venezuelae: a sugar N,N-dimethyltransferase required for dTDP-desosamine biosynthesis | journal = Biochemistry | volume = 47 | issue = 13 | pages = 3982–8 | date = April 2008 | pmid = 18327916 | doi = 10.1021/bi800063j }}</ref> This enzyme [[Chemistry:Catalysis|catalyses]] the following [[Chemistry:Chemical reaction|chemical reaction]]

: 2 S-adenosyl-L-methionine + dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose <math>\rightleftharpoons</math> 2 S-adenosyl-L-homocysteine + dTDP-3-dimethylamino-3,4,6-trideoxy-alpha-D-glucopyranose

The enzyme is involved in the biosynthesis of [[Chemistry:Desosamine|desosamine]].

== References ==
{{reflist}}

== External links ==
* {{MeshName|DTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose+N,N-dimethyltransferase}}

{{One carbon transferases}}
{{Enzymes}}

[[Category:EC 2.1.1]]

{{Sourceattribution|DTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase}}