View source for Biology:GlcA-beta-(1-2)-D-Man-alpha-(1-3)-D-Glc-beta-(1-4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol 4-beta-mannosyltransferase

{{Short description|Class of enzymes}}
{{Infobox enzyme
| Name       = GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol 4-beta-mannosyltransferase
| EC_number  = 2.4.1.251
| CAS_number =
| GO_code    = 
| image      = 
| width      = 
| caption    =  
}}
'''GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol 4-beta-mannosyltransferase''' ({{EC number|2.4.1.251}}, ''GumI'') is an [[Biology:Enzyme|enzyme]] with [[Biology:List of enzymes|systematic name]] ''GDP-mannose:GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol 4-beta-mannosyltransferase''.<ref>{{cite journal | vauthors = Katzen F, Ferreiro DU, Oddo CG, Ielmini MV, Becker A, Pühler A, Ielpi L | title = Xanthomonas campestris pv. campestris gum mutants: effects on xanthan biosynthesis and plant virulence | journal = Journal of Bacteriology | volume = 180 | issue = 7 | pages = 1607–17 | date = April 1998 | pmid = 9537354 | pmc = 107069 }}</ref><ref>{{cite journal | vauthors = Ielpi L, Couso RO, Dankert MA | title = Sequential assembly and polymerization of the polyprenol-linked pentasaccharide repeating unit of the xanthan polysaccharide in Xanthomonas campestris | journal = Journal of Bacteriology | volume = 175 | issue = 9 | pages = 2490–500 | date = May 1993 | pmid = 7683019 | pmc = 204549 }}</ref><ref>{{cite journal | vauthors = Kim SY, Kim JG, Lee BM, Cho JY | title = Mutational analysis of the gum gene cluster required for xanthan biosynthesis in Xanthomonas oryzae pv oryzae | journal = Biotechnology Letters | volume = 31 | issue = 2 | pages = 265–70 | date = February 2009 | pmid = 18854951 | doi = 10.1007/s10529-008-9858-3 }}</ref> This enzyme [[Chemistry:Catalysis|catalyses]] the following [[Chemistry:Chemical reaction|chemical reaction]]

: GDP-mannose + GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol <math>\rightleftharpoons</math> GDP + D-Man-beta-(1->4)- GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol

The enzyme is involved in the biosynthesis of the exopolysaccharide xanthan.

== References ==
{{reflist}}

== External links ==
* {{MeshName|GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol+4-beta-mannosyltransferase}}

{{Glycosyltransferases}}
{{Enzymes}}

[[Category:EC 2.4.1]]

{{Sourceattribution|GlcA-beta-(1-2)-D-Man-alpha-(1-3)-D-Glc-beta-(1-4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol 4-beta-mannosyltransferase}}