Biology:Host factor

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Host factor (sometimes known as risk factor)[1] is a medical term referring to the traits of an individual person or animal that affect susceptibility to disease, especially in comparison to other individuals.[2] The term arose in the context of infectious disease research, in contrast to "organism factors", such as the virulence and infectivity of a microbe. Host factors that may vary in a population and affect disease susceptibility can be innate or acquired. Some examples: [1]

  • general health
  • psychological characteristics and attitude
  • nutritional state
  • social ties
  • previous exposure to the organism or related antigens
  • haplotype or other specific genetic differences of immune function
  • substance abuse
  • race


The term is now used in oncology and many other medical contexts related to individual differences of disease vulnerability.

See also

References