Biology:GEFT
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RAC/CDC42 exchange factor, also known as GEFT, is a human gene.[1]
Interactions
GEFT has been shown to interact with RHOA.[2]
References
- ↑ "Entrez Gene: GEFT RAC/CDC42 exchange factor". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=115557.
- ↑ "p63RhoGEF and GEFT are Rho-specific guanine nucleotide exchange factors encoded by the same gene". Naunyn Schmiedebergs Arch. Pharmacol. 369 (5): 540–6. May 2004. doi:10.1007/s00210-004-0926-5. PMID 15069594.
Further reading
- "Structure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs.". Science 318 (5858): 1923–7. 2008. doi:10.1126/science.1147554. PMID 18096806.
- "The Rho-family guanine nucleotide exchange factor GEFT enhances retinoic acid- and cAMP-induced neurite outgrowth.". J. Neurosci. Res. 83 (7): 1151–9. 2006. doi:10.1002/jnr.20814. PMID 16496360.
- "Modulation of muscle regeneration, myogenesis, and adipogenesis by the Rho family guanine nucleotide exchange factor GEFT.". Mol. Cell. Biol. 25 (24): 11089–101. 2006. doi:10.1128/MCB.25.24.11089-11101.2005. PMID 16314529.
- "The guanine nucleotide exchange factor p63RhoGEF, a specific link between Gq/11-coupled receptor signaling and RhoA.". J. Biol. Chem. 280 (12): 11134–9. 2005. doi:10.1074/jbc.M411322200. PMID 15632174.
- "GEFT, a Rho family guanine nucleotide exchange factor, regulates neurite outgrowth and dendritic spine formation.". J. Biol. Chem. 279 (44): 45824–32. 2004. doi:10.1074/jbc.M406216200. PMID 15322108.
- "p63RhoGEF and GEFT are Rho-specific guanine nucleotide exchange factors encoded by the same gene.". Naunyn Schmiedebergs Arch. Pharmacol. 369 (5): 540–6. 2004. doi:10.1007/s00210-004-0926-5. PMID 15069594.
- "A Rac/Cdc42-specific exchange factor, GEFT, induces cell proliferation, transformation, and migration.". J. Biol. Chem. 278 (15): 13207–15. 2003. doi:10.1074/jbc.M208896200. PMID 12547822.
- "Human p63RhoGEF, a novel RhoA-specific guanine nucleotide exchange factor, is localized in cardiac sarcomere.". J. Cell Sci. 115 (Pt 3): 629–40. 2002. doi:10.1242/jcs.115.3.629. PMID 11861769.