ARGminer

From HandWiki
Short description: Biological database
ARGminer
Content
DescriptionDatabase focused on crowd-sourced curation of ARG pulled from multiple sources.
Data types
captured
Antimicrobial resistance
OrganismsBacteria
Access
Websitebench.cs.vt.edu/argminer
Miscellaneous
Bookmarkable
entities
yes

ARGminer is database that focuses on the novel method of crowd-sourced curation over manual curation of Antibiotic Resistance Genes (ARG) pulled from a multiple sources such as CARD, ARDB, NDARO, DeepARG, Uniprot, ResFinder, and SARG.[1] Additionally, due to the existence of Mobile Genetic Elements (MGE), ARGminer also interfaces with PATRIC and ACLAME.[1] ARGminer annotated genes using their gene name, antibiotic category, resistance mechanism, evidence for mobility and occurrence in clinically important bacterial strains.[1] There are two groups of crowd-sourced curators. One was hired on Amazon Mechanical Turk which offers a broad audience of crowd-sourced experts and non-experts that can annotate for monetary reward. Due to the presence of mixed expertise, each user is only allowed maximum 20 annotations. The other group is a graduate-level microbiology class.[1]

See also

References

  1. 1.0 1.1 1.2 1.3 Zhang, L.; Vikesland, P. J.; Pruden, A.; Heath, L. S.; Riquelme, M. V.; Garner, E.; Guron, G. K. P.; Arango-Argoty, G. A. (2019-03-06). "ARGminer: A web platform for crowdsourcing-based curation of antibiotic resistance genes" (in en). bioRxiv: 274282. doi:10.1101/274282. https://www.biorxiv.org/content/10.1101/274282v2.