Biography:Baek Sung-hee

Short description: South Korean molecular geneticist (born 1970)

Sung Hee Baek
백성희
Born	1970 (age 53–54)
Nationality	South Korean
Alma mater	Seoul National University
Known for	Genetic research
Korean name
Hangul	백성희
Revised Romanization	Baek Seong-hui
McCune–Reischauer	Paek Sǒnghŭi
Scientific career
Fields	Molecular and cellular genetics
Institutions	Seoul National University

Doctor Baek Sung-hee (born 1970) is a South Korean scientist specialising in molecular genetics. Her work is focused on the chromatin dynamics and epigenetic regulatory mechanism in cancer. She received her BS, MS, and Ph.D. degrees from Seoul National University. Following her postdoctoral research in Michael Rosenfeld’s lab at HHMI and following research assistant professor at HHMI, she joined the faculty of Seoul National University in 2003, and now works as an associate professor. Dr. Baek received numerous awards and honors, including the L’Oreal-UNESCO for Women in Science Award.

Awards

• 2005 L’OREAL-UNESCO for Women in Science Award
• 2012 The Women in Science and Technology Award 2012, Korea Science and Engineering Foundation
• 2015 Kyung-Ahm Prize

Publications

• Lee, Ji Min; Lee, Jason S.; Kim, Hyunkyung; Kim, Kyeongkyu; Park, Hyejin; Kim, Ji-Young; Lee, Seung Hoon; Kim, Ik Soo et al. (2012). "EZH2 Generates a Methyl Degron that is Recognized by the DCAF1/DDB1/CUL4 E3 Ubiquitin Ligase Complex". Molecular Cell 48 (4): 572–86. doi:10.1016/j.molcel.2012.09.004. PMID 23063525. 
• Kim, Ik Soo; Lee, Minkyoung; Park, Koog Chan; Jeon, Yoon; Park, Joo Hyeon; Hwang, Eun Ju; Jeon, Tae Im; Ko, Seoyoung et al. (2012). "Roles of Mis18α in Epigenetic Regulation of Centromeric Chromatin and CENP-A Loading". Molecular Cell 46 (3): 260–73. doi:10.1016/j.molcel.2012.03.021. PMID 22516971. 
• Kim, Hyunkyung; Lee, Ji Min; Lee, Gina; Bhin, Jinhyuk; Oh, Se Kyu; Kim, Kyeongkyu; Pyo, Ki Eun; Lee, Jason S. et al. (2011). "DNA Damage-Induced RORα is Crucial for p53 Stabilization and Increased Apoptosis". Molecular Cell 44 (5): 797–810. doi:10.1016/j.molcel.2011.09.023. PMID 22152482. 
• Lee, Jason S.; Kim, Yunho; Bhin, Jinhyuk; Shin, Hi-Jai R.; Nam, Hye Jin; Lee, Seung Hoon; Yoon, Jong-Bok; Binda, Olivier et al. (2011). "Hypoxia-induced methylation of a pontin chromatin remodeling factor". Proceedings of the National Academy of Sciences 108 (33): 13510–5. doi:10.1073/pnas.1106106108. PMID 21825155. Bibcode: 2011PNAS..10813510L. 
• Baek, Sung Hee (2011). "When Signaling Kinases Meet Histones and Histone Modifiers in the Nucleus". Molecular Cell 42 (3): 274–84. doi:10.1016/j.molcel.2011.03.022. PMID 21549306. 
• Lee, Jason S.; Kim, Yunho; Kim, Ik Soo; Kim, Bogyou; Choi, Hee June; Lee, Ji Min; Shin, Hi-Jai R.; Kim, Jung Hwa et al. (2010). "Negative Regulation of Hypoxic Responses via Induced Reptin Methylation". Molecular Cell 39 (1): 71–85. doi:10.1016/j.molcel.2010.06.008. PMID 20603076. 
• Lee, Ji Min; Kim, Ik Soo; Kim, Hyunkyung; Lee, Jason S.; Kim, Kyeongkyu; Yim, Hwa Young; Jeong, Jiyeong; Kim, Jung Hwa et al. (2010). "RORα Attenuates Wnt/β-Catenin Signaling by PKCα-Dependent Phosphorylation in Colon Cancer". Molecular Cell 37 (2): 183–95. doi:10.1016/j.molcel.2009.12.022. PMID 20122401. 
• Baek, Sung Hee (2008). "When ATPases Pontin and Reptin Met Telomerase". Developmental Cell 14 (4): 459–61. doi:10.1016/j.devcel.2008.03.018. PMID 18410720. 
• Kim, Jung Hwa; Lee, Ji Min; Nam, Hee June; Choi, Jung Woo; Yang, Jung Woo; Lee, Jason S.; Kim, Mi Hyang; Kim, Su-Il et al. (2007). "SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells". Proceedings of the National Academy of Sciences 104 (52): 20793–8. doi:10.1073/pnas.0710343105. PMID 18087039. Bibcode: 2007PNAS..10420793K. 
• Kim, Jung Hwa; Choi, Hee June; Kim, Bogyou; Kim, Mi Hyang; Lee, Ji Min; Kim, Ik Soo; Lee, Moon Hee; Choi, Soo Joon et al. (2006). "Roles of sumoylation of a reptin chromatin-remodelling complex in cancer metastasis". Nature Cell Biology 8 (6): 631–9. doi:10.1038/ncb1415. PMID 16699503. 
• Zhu, Ping; Baek, Sung Hee; Bourk, Eliot M.; Ohgi, Kenneth A.; Garcia-Bassets, Ivan; Sanjo, Hideki; Akira, Shizuo; Kotol, Paul F. et al. (2006). "Macrophage/Cancer Cell Interactions Mediate Hormone Resistance by a Nuclear Receptor Derepression Pathway". Cell 124 (3): 615–29. doi:10.1016/j.cell.2005.12.032. PMID 16469706. 
• Baek, Sung Hee; Ohgi, Kenneth A.; Nelson, Charles A.; Welsbie, Derek; Chen, Charlie; Sawyers, Charles L.; Rose, David W.; Rosenfeld, Michael G. (2006). "Ligand-specific allosteric regulation of coactivator functions of androgen receptor in prostate cancer cells". Proceedings of the National Academy of Sciences 103 (9): 3100–5. doi:10.1073/pnas.0510842103. PMID 16492776. Bibcode: 2006PNAS..103.3100B. 
• Kim, Jung Hwa; Kim, Bogyou; Cai, Ling; Choi, Hee June; Ohgi, Kenneth A.; Tran, Chris; Chen, Charlie; Chung, Chin Ha et al. (2005). "Transcriptional regulation of a metastasis suppressor gene by Tip60 and β-catenin complexes". Nature 434 (7035): 921–6. doi:10.1038/nature03452. PMID 15829968. Bibcode: 2005Natur.434..921K. 
• Kioussi, Chrissa; Briata, Paola; Baek, Sung Hee; Rose, David W.; Hamblet, Natasha S.; Herman, Thomas; Ohgi, Kenneth A.; Lin, Chijen et al. (2002). "Identification of a Wnt/Dvl/β-Catenin → Pitx2 Pathway Mediating Cell-Type-Specific Proliferation during Development". Cell 111 (5): 673–85. doi:10.1016/S0092-8674(02)01084-X. PMID 12464179. 
• Baek, Sung Hee; Ohgi, Kenneth A.; Rose, David W.; Koo, Edward H.; Glass, Christopher K.; Rosenfeld, Michael G. (2002). "Exchange of N-CoR Corepressor and Tip60 Coactivator Complexes Links Gene Expression by NF-κB and β-Amyloid Precursor Protein". Cell 110 (1): 55–67. doi:10.1016/S0092-8674(02)00809-7. PMID 12150997. 

External links

• SBAEK LAB.