Biography:Charles E. Warren

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Short description: American glycobiologist (1962–2005)
Charles E. Warren
CharlesEWarren photo.png
Born
Guildford, U.K.
DiedJuly 30, 2005(2005-07-30) (aged 42)
Calgary, Alberta, Canada
Alma mater
Known forGlycobiology
Scientific career
FieldsGlycobiology
InstitutionsNew Hampshire University
Doctoral advisorRaymond Dwek

Charles E. Warren (September 17, 1962 – July 30, 2005)[1] was an assistant professor of biochemistry and molecular biology at the University of New Hampshire.

Early life and education

Warren was born on September 17, 1962, in Guildford, UK. He was son of Joan (Staples) Warren and the late Charles Peter Warren. He was educated at Oxford University, where he received his PhD in 1989 under the mentorship of Raymond Dwek, an eminent early leader in glycobiology. His thesis was entitled Glycosylation in Mice and Rats.[full citation needed]

Research

After graduation he helped establish the first commercially focused effort in glycotechnology: Oxford Glycosystems, Ltd.[2] He subsequently moved to Toronto, Canada, to broaden his interest in glycosyltransferase and spent his postdoctoral time with Dr. Harry Schachter at the Hospital for Sick Children in Toronto, and two years later across the street with Dr. Jim Dennis[3] at the Lunenfeld-Tanenbaum Research Institute. Charles Warren moved to the University of New Hampshire in 2002 as an assistant professor in the Department of Biochemistry and Molecular Biology.

He conducted research on the structure-function relationships of glycosylation. These specific efforts focused on evolution, animal development and human diseases.[4][5] He used C. elegans as his model organism.[6][7]

Awards

After only three years at the University of New Hampshire, he was nominated for a named professorship, the Class of 1944 Award. This university-wide award recognizes outstanding faculty members.[8]

Death

Charles Warren died on July 30, 2005, in a paragliding accident.[1]

Warren Workshops

Since 2006, Warren Workshops are held every second years in Warren's memory. The initial purpose of the Warren Workshop series on Glycoconjugate Analysis was to bring together concerned analysts in the field to discuss the various methodologies in use with the aim to share and appraise protocols for carbohydrate sequencing. Discussion among the experts in the discipline would hopefully lead to establishing a working framework and course of action to bring unanimity to the goals and requirements of glycoconjugate structural analysis. The growing need, aspirations of automation and high throughput analysis, made open discussion among experts very timely and important.

WW-I, July 6–9, 2006, UNH Glycomics Center, Durham, NH, USA; Organiser: Vern Reinhold [9]

WW-II, July 9–12, 2008, UNH Glycomics Center, Durham, NH, USA; Organiser: Vern Reinhold

WW-III, August 27–30, 2010, Hindasgarden Conference Center, Hindås, Sweden; Organiser: Niclas G. Karlsson[10]

WW-IV, August 8–11, 2012, CCRC,[11] Athens, Georgia USA; Organisers: Mike Tiemeyer [12] and Lance Wells

WW-V, August 6–9, 2014, University of Galway, Ireland; Organisers: Rob Woods[13] and Pauline Rudd

WW-VI, August 24–26, 2016, Sapporo University, Japan; Organisers: Kiyoko Aoki-Kinoshita[14] and Hisashi Narimatsu

WW-VII, August 15–18, 2018, Boston University, Massachusetts, USA; Organisers: Joseph Zaia[15] and Catherine Costello[16]

WW-VIII, originally planned in August 2020, Grenoble University, France; Organisers: Anne Imberty,[17] Sylvie Ricard-Blum [18] and Frederique Lisacek,[19] was postponed due to the COVID-19 pandemics. It became a joint event with the Glyco-bioinformatics Symposium of the Beilstein Institute for the Advancement of Chemical Sciences, held on-line, June 23-25, 2021.

WW-IX, is being held in conjunction with the 4th AustralAsian Glycoscience Symposium, 22nd-25th of November 2022, Gold Coast, QLD, Australia. Organisers: Daniel Kolarich,[20] Nicholas Scott.[21]

References

  1. 1.0 1.1 "Paragliding Accident in Canada". http://www.unh.edu/delete/news/news_releases/2005/august/kb_050801warren.html. 
  2. "Oxford University's first spin-off company". https://www2.bioch.ox.ac.uk/glycob/. 
  3. "Dr Jim Dennis". http://www.lunenfeld.ca/researchers/dennis. 
  4. Dennis, Jim W; Granovsky, Maria; Warren, Charles E (1999). "Protein glycosylation in development and disease". BioEssays 21 (5): 412–421. doi:10.1002/(SICI)1521-1878(199905)21:5<412::AID-BIES8>3.0.CO;2-5. PMID 10376012. 
  5. Dennis, Jim W; Granovsky, Maria; Warren, Charles E (1999). "Glycoprotein glycosylation and cancer progression". Biochim Biophys Acta 1473 (1): 21–34. doi:10.1016/s0304-4165(99)00167-1. PMID 10580127. 
  6. Warren, Charles E; Krizus, Aldis; Dennis, Jim W (2001). "Complementary expression patterns of six nonessential Caenorhabditis elegans core 2/I N-acetylglucosaminyltransferase homologues". Glycobiology 11 (11): 979–988. doi:10.1093/glycob/11.11.979. PMID 11744632. 
  7. Warren, Charles E; Krizus, Aldis; Roy, Peter J; Culotti, Joseph G; Dennis, Jim W (2002). "Complementary expression patterns of six nonessential Caenorhabditis elegans core 2/I N-acetylglucosaminyltransferase homologues". J Biol Chem 277 (25): 22829–38. doi:10.1074/jbc.M201390200. PMID 11937505. 
  8. "Professorship at UNH". https://www.unh.edu/provost/faculty-professorships-and-chairs. 
  9. "Prof. Vernon Reinhold". 2017-11-21. https://colsa.unh.edu/person/vernon-reinhold. 
  10. "Niclas Karlsson research group". https://biomedicine.gu.se/ominst/avd/medkem/forskare/niclas-karlsson. 
  11. "Complex Carbohydrate Research Center". https://www.ccrc.uga.edu/. 
  12. "Tiemeyer lab". https://www.ccrc.uga.edu/~mtiemeyer/. 
  13. "About the creators of GLYCAM-Web". http://glycam.org/docs/aboutus/. 
  14. "Kiyoko Aoki-Kinoshita". https://www.soka.ac.jp/en/faculty-profiles/kiyoko-kinoshita/. 
  15. "Zaia research group". http://www.bumc.bu.edu/zaia/. 
  16. "Catherine E. Costello". http://www.bumc.bu.edu/msr/catherine-e-costello-director/. 
  17. "Anne Imberty's group". https://cermav.grenoble.cnrs.fr/en/the-teams/structural-and-molecular-glycobiology/. 
  18. "Sylvie Ricard-Blum's group". http://icbms.univ-lyon1.fr/aspe/. 
  19. "Frederique Lisacek's group". https://www.sib.swiss/frederique-lisacek-group/. 
  20. https://experts.griffith.edu.au/7126-daniel-kolarich Daniel Kolarich
  21. https://findanexpert.unimelb.edu.au/profile/756128-nichollas-scott Nicholas Scott