Biography:Friedhelm Hummel

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Short description: German neuroscientist and neurologist
Professor

Friedhelm Christoph Hummel
EPFL Friedhelm Hummel 2016.jpg
Friedhelm Hummel in 2016
Born
Laichingen, Germany
CitizenshipGermany
Known forNeurorehabilitation
AwardsFelgenhauer Symposiums Prize
Prize of the German Society of Neurotraumatology and Clinical Neurorehabilitation
Dr. Martini Prize
Academic background
EducationMedicine
Alma materUniversity of Tübingen
University of Bordeaux
ThesisElastische Veränderungen durch semantische klassische Konditionierung und ihre elektrokortikalen Korrelate: eine Studie langsamer Potentiale (2000)
Academic advisorsNiels Birbaumer
Academic work
DisciplineNeuroscience
Sub-disciplineNeurorehabilitation
InstitutionsEPFL (École Polytechnique Fédérale de Lausanne)
Main interestsStroke recovery
Motor control
Neuroplasticity
Non-invasive brain stimulation
Structural and functional neuroimaging
Websitehttps://www.epfl.ch/labs/hummel-lab/

Friedhelm Christoph Hummel (born 1969 in Laichingen, Germany) is a German neuroscientist and neurologist. A full professor at École Polytechnique Fédérale de Lausanne, he is the Defitech Chair of Clinical Neuroengineering, and the head of the Hummel Laboratory at EPFL's School of Life Sciences.[1][2] He also is an associate professor of clinical neuroscience at the University of Geneva.[3]

Career

Hummel studied medicine at University of Tübingen and at Bordeaux Segalen University, graduating in 1998. He then joined the Department of Neurology at the University of Tübingen as a medical resident and researcher.[4] He earned his medical doctor degree in 2000 for his work on Plastische Veränderungen durch semantische klassische Konditionierung und ihre elektrokortikalen Korrelate: eine Studie langsamer Potentiale (Plastic changes through semantic classical conditioning and their electrocortical correlates: a study of slow potentials).[5]

In 2003, he received a Feodor Lynen award from the Alexander von Humboldt Foundation to join Leonardo Cohen's Human Cortical Physiology and Neurorehabilitation Section (NINDS) at the National Institutes of Health (NIH) at Bethesda.[6][7] There he worked on the first successful application of transcranial direct current stimulation (tDCS) in stroke patients.[8] In 2005, he returned as researcher and medical resident to the Department of Neurology at Tübingen,[9] and, in 2006, to the University Medical Center Hamburg-Eppendorf to finish his residency.[10] In 2006, he founded the Brain Imaging and Neurostimulation (BINS) Laboratory at Hamburg, became a certified in 2007,[11][12] co-chairman at the Centre for Sleep Medicine in 2008, senior neurologist in 2013, and vice-director of the Department of neurology in 2013.[13][14]

Since 2016 he holds the Defitech Chair for Clinical Neuroengineering as full professor, is the director of the Hummel Laboratory at the Centre for Neuroprosthetics (CNP) and the Brain Mind Institute (BMI), both at EPFL.[1][2] Furthermore, he holds an associate professorship of clinical neuroscience at the University of Geneva.[3]

Research

Hummel's research targets the fields of systems and translational clinical neuroscience with three main areas of focus.

The first focus is on using multimodal imaging and behavioral measures to study neuroplasticity, neuronal control of sensorimotor functions, learning, and cognitive functions in healthy and neurological disorders, such as stroke, mild cognitive impairment (MCI) or traumatic brain injury (TBI).

The second main focus is on developing innovative non-invasive interventional strategies based on neurotechnology,[15][16][17] such as brain stimulation[18][19] to support patients' residual functions and enhance recovery.[20][21] He has been involved in the application of non-invasive brain stimulation in stroke.[22][23]

The third focus is the use of multimodal imaging to predict outcome and course of recovery after a stroke (Koch et al. 2021 Brain; Egger et al. 2021 Stroke), a prerequisite for personalized treatment strategies.[24][25]

His research has been featured in news outlets such as NZZ,[26] Le Nouvelliste, Physics World,[27] Der Spiegel,[28] and Focus.[29]

Distinctions

Hummel is the recipient of the 2015 Felgenhauer Symposiums Prize of the German Neurological Society and the Felgenhauer Foundation;[30] the 2013 prize of the German Society of Neurotraumatology and Clinical Neurorehabilitation;[31] the 2010 Dr. Martini Prize;[32] the 2005 Susanne Klein-Vogelbach Prize;[33] 2005 Fellows Award for Research Excellence by the National Institutes of Health; and the 2003 Feodor Lynen Research Fellowship Award by the Alexander von Humboldt Foundation.[31]

He is a member of the German Neurological Society,[34] the Society for Neuroscience, and the Society for the Neural Control of Movement.[35]

Selected works

References

  1. ↑ 1.0 1.1 "Hummel Lab" (in en-GB). https://www.epfl.ch/labs/hummel-lab/. 
  2. ↑ 2.0 2.1 "Brexit: closer cooperation with the UK cannot replace participation in Horizon 2020 | ETH-Board". https://www.ethrat.ch/en/medien-medienmitteilungen/brexit-engere-zusammenarbeit-mit-grossbritannien-kann-teilnahme-horizon-2020-nicht-ersetzen. 
  3. ↑ 3.0 3.1 "Friedhelm Hummel | Campus Biotech". https://www.campusbiotech.ch/en/node/416. 
  4. ↑ Rau, Cornelia; Plewnia, Christian; Hummel, Friedhelm; Gerloff, Christian (2003-10-01). "Event-related desynchronization and excitability of the ipsilateral motor cortex during simple self-paced finger movements" (in en). Clinical Neurophysiology 114 (10): 1819–1826. doi:10.1016/S1388-2457(03)00174-3. ISSN 1388-2457. PMID 14499743. https://www.sciencedirect.com/science/article/abs/pii/S1388245703001743. 
  5. ↑ Hummel, Friedhelm C. (2000). Plastische Veränderungen durch semantische klassische Konditionierung und ihre elektrokortikalen Korrelate eine Studie langsamer Potentiale. Tübingen. https://rds-tue.ibs-bw.de/link?kid=1158454910. 
  6. ↑ Fridman, E. A. (2004-01-14). "Reorganization of the human ipsilesional premotor cortex after stroke" (in en). Brain 127 (4): 747–758. doi:10.1093/brain/awh082. ISSN 1460-2156. PMID 14749291. https://academic.oup.com/brain/article-lookup/doi/10.1093/brain/awh082. 
  7. ↑ Hummel, F. (2005-01-05). "Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke" (in en). Brain 128 (3): 490–499. doi:10.1093/brain/awh369. ISSN 1460-2156. PMID 15634731. 
  8. ↑ Hummel, Friedhelm C; Cohen, Leonardo G (August 2006). "Non-invasive brain stimulation: a new strategy to improve neurorehabilitation after stroke?". The Lancet Neurology 5 (8): 708–712. doi:10.1016/s1474-4422(06)70525-7. ISSN 1474-4422. http://dx.doi.org/10.1016/s1474-4422(06)70525-7. 
  9. ↑ Gandiga, Prateek C.; Hummel, Friedhelm C.; Cohen, Leonardo G. (April 2006). "Transcranial DC stimulation (tDCS): A tool for double-blind sham-controlled clinical studies in brain stimulation" (in en). Clinical Neurophysiology 117 (4): 845–850. doi:10.1016/j.clinph.2005.12.003. PMID 16427357. https://linkinghub.elsevier.com/retrieve/pii/S1388245705005079. 
  10. ↑ Heise, K.-F; Gerloff, C; Hummel, F (September 2007). "Nicht invasive kortikale Stimulation als adjuvante Therapie zur Unterstützung der funktionellen Erholung nach Schlaganfall" (in de). Physioscience 3 (3): 99–108. doi:10.1055/s-2007-963363. ISSN 1860-3092. http://www.thieme-connect.de/DOI/DOI?10.1055/s-2007-963363. 
  11. ↑ Nitsche, Michael A.; Cohen, Leonardo G.; Wassermann, Eric M.; Priori, Alberto; Lang, Nicolas; Antal, Andrea; Paulus, Walter; Hummel, Friedhelm et al. (July 2008). "Transcranial direct current stimulation: State of the art 2008" (in en). Brain Stimulation 1 (3): 206–223. doi:10.1016/j.brs.2008.06.004. PMID 20633386. https://linkinghub.elsevier.com/retrieve/pii/S1935861X08000405. 
  12. ↑ Sauseng, Paul; Klimesch, Wolfgang; Heise, Kirstin F.; Gruber, Walter R.; Holz, Elisa; Karim, Ahmed A.; Glennon, Mark; Gerloff, Christian et al. (2009-11-17). "Brain Oscillatory Substrates of Visual Short-Term Memory Capacity" (in en). Current Biology 19 (21): 1846–1852. doi:10.1016/j.cub.2009.08.062. ISSN 0960-9822. PMID 19913428. 
  13. ↑ Hummel, Friedhelm Christoph; Gerloff, Christian (2011). "Zukunft der Neuromodulation" (in en). https://infoscience.epfl.ch/record/224097. 
  14. ↑ Lefaucheur, Jean-Pascal; André-Obadia, Nathalie; Antal, Andrea; Ayache, Samar S.; Baeken, Chris; Benninger, David H.; Cantello, Roberto M.; Cincotta, Massimo et al. (November 2014). "Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS)" (in en). Clinical Neurophysiology 125 (11): 2150–2206. doi:10.1016/j.clinph.2014.05.021. PMID 25034472. https://linkinghub.elsevier.com/retrieve/pii/S138824571400296X. 
  15. ↑ Coscia, Martina; Wessel, Maximilian J; Chaudary, Ujwal; Millán, José del R; Micera, Silvestro; Guggisberg, Adrian; Vuadens, Philippe; Donoghue, John et al. (2019-07-01). "Neurotechnology-aided interventions for upper limb motor rehabilitation in severe chronic stroke". Brain 142 (8): 2182–2197. doi:10.1093/brain/awz181. ISSN 0006-8950. PMID 31257411. PMC 6658861. https://doi.org/10.1093/brain/awz181. 
  16. ↑ Micera, Silvestro; Caleo, Matteo; Chisari, Carmelo; Hummel, Friedhelm C.; Pedrocchi, Alessandra (2020-02-19). "Advanced Neurotechnologies for the Restoration of Motor Function" (in English). Neuron 105 (4): 604–620. doi:10.1016/j.neuron.2020.01.039. ISSN 0896-6273. PMID 32078796. https://www.cell.com/neuron/abstract/S0896-6273(20)30066-0. 
  17. ↑ Raffin, Estelle; Salamanca-Giron, Roberto F.; Hummel, Friedhelm Christoph (2020-01-01). "Perspectives: Hemianopia—Toward Novel Treatment Options Based on Oscillatory Activity?" (in en). Neurorehabilitation and Neural Repair 34 (1): 13–25. doi:10.1177/1545968319893286. ISSN 1545-9683. https://doi.org/10.1177/1545968319893286. 
  18. ↑ Wessel, Maximilian J.; Draaisma, Laurijn R.; de Boer, Anne F. W.; Park, Chang-hyun; Maceira-Elvira, Pablo; Durand-Ruel, Manon; Koch, Philipp J.; Morishita, Takuya et al. (2020-07-08). "Cerebellar transcranial alternating current stimulation in the gamma range applied during the acquisition of a novel motor skill" (in en). Scientific Reports 10 (1): 11217. doi:10.1038/s41598-020-68028-9. ISSN 2045-2322. PMID 32641706. PMC 7343806. https://www.nature.com/articles/s41598-020-68028-9. 
  19. ↑ Salamanca-giron, Roberto F.; Raffin, Estelle; Zandvliet, Sarah B.; Seeber, Martin; Michel, Christoph M.; Sauseng, Paul; Huxlin, Krystel R.; Hummel, Friedhelm C. (2021-10-15). "Enhancing visual motion discrimination by desynchronizing bifocal oscillatory activity" (in en). NeuroImage 240: 118299. doi:10.1016/j.neuroimage.2021.118299. ISSN 1053-8119. https://www.sciencedirect.com/science/article/pii/S1053811921005759. 
  20. ↑ Raffin, Estelle; Hummel, Friedhelm C. (2018-08-01). "Restoring Motor Functions After Stroke: Multiple Approaches and Opportunities" (in en). The Neuroscientist 24 (4): 400–416. doi:10.1177/1073858417737486. ISSN 1073-8584. https://doi.org/10.1177/1073858417737486. 
  21. ↑ Wessel, Maximilian J.; Hummel, Friedhelm C. (2018-06-01). "Non-invasive Cerebellar Stimulation: a Promising Approach for Stroke Recovery?" (in en). The Cerebellum 17 (3): 359–371. doi:10.1007/s12311-017-0906-1. ISSN 1473-4230. https://doi.org/10.1007/s12311-017-0906-1. 
  22. ↑ Hummel, F. (2005-01-05). "Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke". Brain 128 (3): 490–499. doi:10.1093/brain/awh369. ISSN 1460-2156. https://doi.org/10.1093/brain/awh369. 
  23. ↑ Hummel, Friedhelm C.; Cohen, Leonardo G. (2006-08-01). "Non-invasive brain stimulation: a new strategy to improve neurorehabilitation after stroke?" (in English). The Lancet Neurology 5 (8): 708–712. doi:10.1016/S1474-4422(06)70525-7. ISSN 1474-4422. PMID 16857577. https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(06)70525-7/abstract. 
  24. ↑ Koch, Philipp J; Park, Chang-Hyun; Girard, Gabriel; Beanato, Elena; Egger, Philip; Evangelista, Giorgia Giulia; Lee, Jungsoo; Wessel, Maximilian J et al. (2021-07-01). "The structural connectome and motor recovery after stroke: predicting natural recovery". Brain 144 (7): 2107–2119. doi:10.1093/brain/awab082. ISSN 0006-8950. PMID 34237143. PMC 8370413. https://doi.org/10.1093/brain/awab082. 
  25. ↑ Egger, Philip; Evangelista, Giorgia G.; Koch, Philipp J.; Park, Chang-Hyun; Levin-Gleba, Laura; Girard, Gabriel; Beanato, Elena; Lee, Jungsoo et al. (2021-06-01). "Disconnectomics of the Rich Club Impacts Motor Recovery After Stroke". Stroke 52 (6): 2115–2124. doi:10.1161/STROKEAHA.120.031541. https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.031541. 
  26. ↑ Geiser, Eveline (2021-07-15). "Wo Ärzte abwarten müssen, kann künstliche Intelligenz eine Prognose stellen". https://www.nzz.ch/wissenschaft/wo-aerzte-abwarten-muessen-kann-kuenstliche-intelligenz-eine-prognose-stellen-ld.1634821. 
  27. ↑ "Mapping the brain's neural connections can predict recovery after stroke" (in en-GB). 2021-07-13. https://physicsworld.com/mapping-the-brains-neural-connections-can-predict-recovery-after-stroke/. 
  28. ↑ SPIEGEL, Susanne Schäfer, DER (23 April 2015). "Warum ein Schlag auf den Musikknochen so weh tut" (in de). Der Spiegel. https://www.spiegel.de/gesundheit/diagnose/warum-ein-schlag-auf-den-musikknochen-so-weh-tut-a-1028465.html. 
  29. ↑ Online, FOCUS. "Stimulation von Hirnarealen" (in de). https://www.focus.de/wissen/mensch/intelligenz/gehirndoping-mit-strom-stimulation-von-hirnarealen_id_4047440.html. 
  30. ↑ "Awards (2014 - 2015)". https://hahn-institute.de/en/awards. 
  31. ↑ 31.0 31.1 "Third congress on NeuroRehabilitation and Neural Repair". http://www.neurorehabrepair.eu/resources/media/Programma/20190502_ECNR_final_Programme_2019_versie_12_Final_Version.pdf. 
  32. ↑ "Dr. Martini-Preis | Dr.-Martini-Stiftung". 2016-10-23. http://dr-martini-stiftung.de/wissenschaftspreis-medizinpreis-dr-martini-preis/. 
  33. ↑ "SKV-Preis" (in de). http://www.fbl-klein-vogelbach.org/skv-preis.html. 
  34. ↑ "Preise und Ehrungen der DGN auf dem Kongress 2015 - Deutsche Gesellschaft für Neurologie e. V." (in de-DE). https://dgn.org/presse/pressemitteilungen/preise-und-ehrungen-der-dgn-auf-dem-kongress-2015/. 
  35. ↑ "29th NCM Annual Meeting". https://ncm-society.org/wp-content/uploads/2019/04/NCM-2019-program-109-A4-web.pdf. 

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