Biography:Pier Mario Biava

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Short description: Italian occupational doctor
Pier Mario Biava

Pier Mario Biava is an Italian occupational doctor. For several years, he has been researching the connection between cancer and cell differentiation. Currently, He is active at the Institute of Multimedia Scientific Hospitalization and Care in Milan. He is also the author of over 100 scientific publications and six books.[1][2] He is also the co-founder of the Novacell Biotech Company based in Milan, which produces food supplements and cosmetics for the prevention of aging and the onset of degenerative diseases.[3]

Education

Pier Mario Biava received his medical degree from the University of Pavia and went on to specialize in occupational medicine and hygiene at the Universities of Padua and Trieste, respectively.[4]

Research and career

For several years he has been studying the relationship between cancer and cell differentiation:[5] he has identified specific networks of stem cell growth factors,[6] which as epigenetic regulators are able to control the expression of various genes capable of slowing down cellular aging and regenerating different types of tissue without the need for stem cell transplantation.[7]

He has also identified specific networks of differentiation factors capable of reprogramming pathological stem cells, such as cancer and cells of the germinative layer of the epidermis altered in psoriasis. He also emphasized that in order to reprogram altered stem cells or to regenerate a tissue it is necessary to regulate many genes at the same time and not a single gene.[8][9]

Books

  • Cancer and the Search for Lost Meaning: The Discovery of a Revolutionary New Cancer Treatment.[10]
  • Information Medicine: The Revolutionary Cell-Reprogramming Discovery that Reverses Cancer and Degenerative Diseases.[11]

Publications

  • Cancer: A Problem of Developmental Biology; Scientific Evidence for Reprogramming and Differentiation Therapy.[12]
  • Active Fraction from Embryo Fish Extracts Induces Reversion of the Malignant Invasive Phenotype in Breast Cancer through Down-regulation of TCTP and Modulation of E-cadherin/β-catenin Pathway.[13]
  • Autism Spectrum Disorder from the Womb to Adulthood: Suggestions for a Paradigm Shift.[14]
  • The zebrafish embryo derivative affects cell viability of epidermal cells: a possible role in the treatment of psoriasis.[15]
  • Changing the endocrine dependence of breast cancer: data and hypotheses.[16]
  • Exosomes and Cell Communication: From Tumour-Derived Exosomes and Their Role in Tumour Progression to the Use of Exosomal Cargo for Cancer Treatment.[17]

References

  1. ↑ biava. "Pier Mario Biava | Reprogram Cells | Official site" (in en-US). https://www.biava.me/en/. 
  2. ↑ "Pier Mario Biava" (in en). https://www.simonandschuster.com/authors/Pier-Mario-Biava/152387851. 
  3. ↑ Biotech, Novacell. "CELL INTEGRITY e ROYAL CELLS" (in en-US). https://www.novacell.com/en/. 
  4. ↑ Biava, Pier Mario (2009) (in en). Cancer and the Search for Lost Meaning: The Discovery of a Revolutionary New Cancer Treatment. North Atlantic Books. ISBN 978-1-55643-778-6. https://books.google.com/books?id=-nKhQLUNShEC&q=Pier+Mario+Biava+University+of+Pavia&pg=PA151. 
  5. ↑ Jögi, Annika; Vaapil, Marica; Johansson, Martin; Påhlman, Sven (May 2012). "Cancer cell differentiation heterogeneity and aggressive behavior in solid tumors". Upsala Journal of Medical Sciences 117 (2): 217–224. doi:10.3109/03009734.2012.659294. ISSN 0300-9734. PMID 22376239. 
  6. ↑ Biava, Pier Mario (January 2020). "The Use of Stem Cell Differentiation Stage Factors (SCDSFs) Taken from Zebrafish Embryos during Organogenesis and Their Role in Regulating the Gene Expression of Normal and Pathological (Stem) Cells" (in en). International Journal of Molecular Sciences 21 (14): 4914. doi:10.3390/ijms21144914. PMID 32664640. 
  7. ↑ Biava, Pier Mario (January 2020). "The Use of Stem Cell Differentiation Stage Factors (SCDSFs) Taken from Zebrafish Embryos during Organogenesis and Their Role in Regulating the Gene Expression of Normal and Pathological (Stem) Cells" (in en). International Journal of Molecular Sciences 21 (14): 4914. doi:10.3390/ijms21144914. PMID 32664640. 
  8. ↑ Cells, Reprogram (2018-02-10). "How to Reprogram Cancer Stem Cells | Reprogram Cells" (in en-US). https://www.reprogramcells.com/. 
  9. ↑ Gonzalez, Michael J.; Kweh, Mercedes F.; Biava, Pier Mario; Olalde, Jose; Toro, Alondra P.; Goldschmidt-Clermont, Pascal J.; White, Ian A. (2021-03-09). "Evaluation of exosome derivatives as bio-informational reprogramming therapy for cancer". Journal of Translational Medicine 19 (1): 103. doi:10.1186/s12967-021-02768-8. ISSN 1479-5876. PMID 33750417. 
  10. ↑ Biava, Pier Mario (2009). Cancer and the search for lost meaning : the discovery of a revolutionary new cancer treatment. Berkeley, Calif.: North Atlantic Books. ISBN 978-1-55643-778-6. OCLC 232980406. https://www.worldcat.org/oclc/232980406. 
  11. ↑ Laszlo, Ervin (2019). Information medicine : the revolutionary cell-reprogramming discovery that reverses cancer and degenerative diseases. Pier Mario Biava. Rochester, Vermont. ISBN 978-1-62055-822-5. OCLC 1045155599. https://www.worldcat.org/oclc/1045155599. 
  12. ↑ Stewart, Sell; Andrea, Nicolini; Paola, Ferrari; Pier, M. Biava (2016-07-31). "Cancer: A Problem of Developmental Biology; Scientific Evidence for Reprogramming and Differentiation Therapy" (in en). Current Drug Targets 17 (10): 1103–1110. doi:10.2174/1389450116666150907102717. PMID 26343109. https://www.eurekaselect.com/134719/article. Retrieved 2021-05-13. 
  13. ↑ Proietti, Sara; Cucina, Alessandra; Pensotti, Andrea; Biava, Pier Mario; Minini, Mirko; Monti, Noemi; Catizone, Angela; Ricci, Giulia et al. (January 2019). "Active Fraction from Embryo Fish Extracts Induces Reversion of the Malignant Invasive Phenotype in Breast Cancer through Down-Regulation of TCTP and Modulation of E-cadherin/β-catenin Pathway" (in en). International Journal of Molecular Sciences 20 (9): 2151. doi:10.3390/ijms20092151. PMID 31052313. 
  14. ↑ Panisi, Cristina; Guerini, Franca Rosa; Abruzzo, Provvidenza Maria; Balzola, Federico; Biava, Pier Mario; Bolotta, Alessandra; Brunero, Marco; Burgio, Ernesto et al. (February 2021). "Autism Spectrum Disorder from the Womb to Adulthood: Suggestions for a Paradigm Shift" (in en). Journal of Personalized Medicine 11 (2): 70. doi:10.3390/jpm11020070. PMID 33504019. 
  15. ↑ Norata, G. D.; Biava, P. M.; Di Pierro, F. (October 2013). "The zebrafish embryo derivative affects cell viability of epidermal cells: a possible role in the treatment of psoriasis". Giornale Italiano di Dermatologia e Venereologia 148 (5): 479–483. ISSN 0392-0488. PMID 24005140. https://pubmed.ncbi.nlm.nih.gov/24005140. 
  16. ↑ Nicolini, A.; Ferrari, P.; Biava, P. M.; Carpi, A. (2014). "Changing the endocrine dependence of breast cancer: data and hypotheses". Current Medicinal Chemistry 21 (9): 1093–1106. doi:10.2174/0929867321666131201141741. ISSN 1875-533X. PMID 24304277. https://pubmed.ncbi.nlm.nih.gov/24304277. 
  17. ↑ Nicolini, Andrea; Ferrari, Paola; Biava, Pier Mario (2021-02-16). "Exosomes and Cell Communication: From Tumour-Derived Exosomes and Their Role in Tumour Progression to the Use of Exosomal Cargo for Cancer Treatment" (in en). Cancers 13 (4): 822. doi:10.3390/cancers13040822. ISSN 2072-6694. PMID 33669294. 



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