Biography:Ruth R. Wexler
From HandWiki
Short description: American chemist
Ruth Wexler is an American industrial chemist best known as a co-discoverer of apixaban, a marketed anticoagulant; and losartan, a blood pressure treatment.[1]
Ruth R. Wexler | |
|---|---|
| Born | Pikesville, MD |
| Nationality | American |
| Alma mater | University of Pennsylvania |
| Known for | cardiovascular drug development |
| Scientific career | |
| Thesis | (1982) |
| Doctoral advisor | Amos Smith |
Education
Wexler received her B.A. in chemistry from Boston University in 1977, and a Ph.D. in organic chemistry working with Amos B. Smith at the University of Pennsylvania in 1982.[2][3]
Research
Wexler started her career at DuPont in 1982, rising to Executive Director in 1998. She then joined Bristol-Myers Squibb as an Executive Director in 2001, moving eventually to New Jersey to head their cardiovascular research unit.[2] She has worked on targets involved in apoptosis, inflammation, obesity, and coagulation. As of 2018, she has over 215 original research publications.[4]
Awards
- 2015 - E.B. Hershberg Award for Discoveries in Medicinally Active Substances[1]
- 2014 - Inducted into the ACS MEDI Hall of Fame[5]
- 2011 - BMS Ondetti and Cushman Award
- 2004 - Outstanding New Jersey Woman in Research
References
- ↑ 1.0 1.1 Jarvis, Lisa. "E. B. Hershberg Award For Important Discoveries In Medicinally Active Substances | Chemical & Engineering News". https://cen.acs.org/articles/93/i9/E-B-Hershberg-Award-Important.html.
- ↑ 2.0 2.1 "Ruth R. Wexler, Ph.D.". https://www.acsmedchem.org/?nd=Wexler.
- ↑ "Wexler, Ruth | Amos Smith Research Group" (in en). https://www.sas.upenn.edu/smith-group/content/wexler-ruth.
- ↑ Quan, Mimi L.; Pinto, Donald J. P.; Smallheer, Joanne M.; Ewing, William R.; Rossi, Karen A.; Luettgen, Joseph M.; Seiffert, Dietmar A.; Wexler, Ruth R. (2018-05-18). "Factor XIa Inhibitors as New Anticoagulants" (in en). Journal of Medicinal Chemistry 61 (17): 7425–7447. doi:10.1021/acs.jmedchem.8b00173. ISSN 0022-2623. PMID 29775297.
- ↑ "MEDI Hall of Fame Inductees". https://www.acsmedchem.org/?nd=inductees.
 |  |
