Biology:Acanthocystis turfacea chlorella virus 1
| Acanthocystis turfacea chlorella virus 1 | |
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Virus classification 
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| (unranked): | Virus |
| Realm: | Varidnaviria |
| Kingdom: | Bamfordvirae |
| Phylum: | Nucleocytoviricota |
| Class: | Megaviricetes |
| Order: | Algavirales |
| Family: | Phycodnaviridae |
| Genus: | Chlorovirus |
| Species: | Acanthocystis turfacea chlorella virus 1
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Acanthocystis turfacea chlorella virus 1 (ATCV-1), also called Chlorovirus ATCV-1 or Chlorella virus ATCV-1 is a species of giant double-stranded DNA virus in the genus Chlorovirus.
The host of ATCV-1 is Chlorella heliozoae; it was demonstrated that "ATCV-1 neither attaches to nor infects" Chlorella variabilis.[1][2]
Human infection
DNA from ATCV-1 has been isolated from the mucous membranes of the noses of humans. In both humans and mice, the presence of ATCV-1 on the oropharyngeal mucosa was associated with lower scores in tests of cognitive and motor skills.[3][4][5] Injection of purified algal virus ATCV-1 intracranially results in long-lasting cognitive and behavioural effects in mice via induction of inflammatory factors.[6]
References
- ↑ Irina Agarkova; Brigitte Hertel; Xinzheng Zhang; Les Lane; Alexander Tchourbanov; David D. Dunigan; Gerhard Thiel; Michael G. Rossmann et al. (2014). "Dynamic attachment of Chlorovirus PBCV-1 to Chlorella variabilis". Virology 466-467: 95–102. doi:10.1016/j.virol.2014.07.002. PMID 25240455.
- ↑ "SAG 211-6 Chlorella variabilis". http://www.straininfo.net/strains/822477/browser.
- ↑ Yolken, R. H.; Jones-Brando, L.; Dunigan, D. D.; Kannan, G.; Dickerson, F.; Severance, E.; Sabunciyan, S.; Talbot, C. C. et al. (2014). "Chlorovirus ATCV-1 is part of the human oropharyngeal virome and is associated with changes in cognitive functions in humans and mice". Proc Natl Acad Sci U S A 111 (45): 16106–11. doi:10.1073/pnas.1418895111. PMID 25349393. Bibcode: 2014PNAS..11116106Y.
- ↑ Yolken (2015). "Reply to Kjartansdóttir et al.: Chlorovirus ATCV-1 findings not explained by contamination". Proceedings of the National Academy of Sciences 112 (9): E927. doi:10.1073/pnas.1424665112. PMID 25654982. Bibcode: 2015PNAS..112E.927Y.
- ↑ Elizabeth Pennisi (27 October 2014), "Algal virus found in humans, slows brain activity", Science, https://www.science.org/content/article/algal-virus-found-humans-slows-brain-activity?rss=1
- ↑ Marilyn S. Petro; Irina V. Agarkova; Thomas M.Petro (May 2016). "Effect of Chlorovirus ATCV-1 infection on behavior of C57Bl/6 mice". Journal of Neuroimmunology 297: 46–55. doi:10.1016/j.jneuroim.2016.05.009. PMID 27397075. https://www.researchgate.net/publication/302971382.
External links
- "Acanthocystis turfacea chlorella virus 1". NCBI Taxonomy Browser. https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=322019.
Wikidata ☰ Q18657978 entry
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