Biology:Actino-ugpB RNA motif
From HandWiki
| Actino-ugpB | |
|---|---|
 Consensus secondary structure and sequence conservation of Actino-ugpB RNA | |
| Identifiers | |
| Symbol | Actino-ugpB |
| Rfam | RF02927 |
| Other data | |
| RNA type | Gene; sRNA |
| SO | 0001263 |
| PDB structures | PDBe |
The Actino-ugpB RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1]
Actino-ugpB motifs are found in strains of the species Gardnerella vaginalis, within the phylum Actinomycetota.
It is ambiguous whether Actino-ugpB RNAs function as cis-regulatory elements or whether they operate in trans. Many of the RNAs are upstream of the gene 'ugpB', which encodes a protein putatively involved in sugar transport. However, several of the RNAs are not located upstream of a protein-coding gene. Structurally, the motif consists of two hairpins with conserved nucleotides located in the stems and outside of the hairpins, but not in their terminal loops.
References
- ↑ "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. October 2017. doi:10.1093/nar/gkx699. PMID 28977401.
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