Biology:Biothesiometry
Biothesiometry is a noninvasive medical test used to quantify the perception of vibration by measuring its threshold.[1] It is used in neurology and electrophysiology to diagnose a number of conditions, like diabetic neuropathy and erectile dysfunction, where the vibration perception threshold (VPT) would be higher than average.[1][2] The numerical nature of the test can help stage the progression of disease or complications.
The test is done through a biothesiometer, which is composed of a handheld probe wired to a display unit. Both digital and analog types are commercially available, giving the reading on either a dial or a screen.
In a systematic review of screening methods for pediatric diabetic peripheral neuropathies, biothesiometry and fine microfilaments were shown to be the only diagnostic methods with high sensitivity and specificity.[3]
A systematic review showed that there is a strong co-relation between HbA1c values and Vibration Perception Test and could be a predictor for complications in the foot following Diabetic Peripheral Neuropathy.[4]
In a systemic review of modern devices available for the assessment and screening of peripheral neuropathy, digital devices were evaluated to measure tactile sensation, vibration perception, thermal perception and foot skin temperature.[5]
References
- ↑ 1.0 1.1 Mulhall, John P.; Jenkins, Lawrence C. (2017), Mulhall, John P.; Jenkins, Lawrence C., eds., "Biothesiometry" (in en), Atlas of Office Based Andrology Procedures (Cham: Springer International Publishing): pp. 9–14, doi:10.1007/978-3-319-42178-0_2, ISBN 978-3-319-42176-6, http://link.springer.com/10.1007/978-3-319-42178-0_2, retrieved 2022-02-27
- ↑ Davis, E. A.; Jones, T. W.; Walsh, P.; Byrne, G. C. (Sep 1997). "The use of biothesiometry to detect neuropathy in children and adolescents with IDDM". Diabetes Care 20 (9): 1448–1453. doi:10.2337/diacare.20.9.1448. ISSN 0149-5992. PMID 9283795. https://pubmed.ncbi.nlm.nih.gov/9283795.
- ↑ Hirschfeld, Gerrit; von Glischinski, Michael; Blankenburg, Markus; Zernikow, Boris (2014-05-01). "Screening for Peripheral Neuropathies in Children With Diabetes: A Systematic Review" (in en). Pediatrics 133 (5): e1324–e1330. doi:10.1542/peds.2013-3645. ISSN 0031-4005. PMID 24709928. https://publications.aap.org/pediatrics/article/133/5/e1324/32806/Screening-for-Peripheral-Neuropathies-in-Children.
- ↑ Maiya, Arun G.; Parameshwar, Anche; Hande, Manjunath (2020). "Relationship Between Glycated Hemoglobin and Vibration Perception Threshold in Diabetic Peripheral Neuropathy". The International Journal of Lower Extremity Wounds 19 (2): 120–124. doi:10.1177/1534734619882173. ISSN 1552-6941. PMID 31838926. https://pubmed.ncbi.nlm.nih.gov/31838926/.
- ↑ Riddhi, Dasgupta; Jebasingh, Felix; Thomas, Nihal; Kn, Maruthy; Sharma, Sanjay; Saravanan, Bharathi (2022). "NEURO TOUCH: A novel digital device for assessment and screening of peripheral neuropathy" (in en). The Foot 51: 101888. doi:10.1016/j.foot.2021.101888. ISSN 0958-2592. PMID 35255407. https://www.sciencedirect.com/science/article/pii/S0958259221001140.
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