Biology:CEP68
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Centrosomal protein of 68 kDa is a protein that in humans is encoded by the CEP68 gene.[1][2][3][4] CEP68 is required for centrosome cohesion. It decorates fibres emanating from the proximal ends of centrioles. During mitosis, CEP68 dissociates from centrosomes. CEP68 and rootletin depend both on each other for centriole association, and both also require CEP250 for their function.[5]
References
- ↑ "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research 5 (1): 31–9. Feb 1998. doi:10.1093/dnares/5.1.31. PMID 9628581.
- ↑ Sanger Centre, The; Washington University Genome Sequencing Cente, The (Nov 1998). "Toward a complete human genome sequence". Genome Research 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
- ↑ "Proteomic characterization of the human centrosome by protein correlation profiling". Nature 426 (6966): 570–4. Dec 2003. doi:10.1038/nature02166. PMID 14654843. Bibcode: 2003Natur.426..570A.
- ↑ "Entrez Gene: CEP68 centrosomal protein 68kDa". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23177.
- ↑ "Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion". Journal of Cell Science 120 (Pt 24): 4321–31. Dec 2007. doi:10.1242/jcs.020248. PMID 18042621.
External links
- Human CEP68 genome location and CEP68 gene details page in the UCSC Genome Browser.
Further reading
- "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Research 9 (3): 99–106. Jun 2002. doi:10.1093/dnares/9.3.99. PMID 12168954.
- "Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants". Molecular Vision 8: 205–20. Jun 2002. PMID 12107410.
- "Rate of evolution in brain-expressed genes in humans and other primates". PLOS Biology 5 (2): e13. Feb 2007. doi:10.1371/journal.pbio.0050013. PMID 17194215.
- "Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells". Proteomics 7 (14): 2384–97. Jul 2007. doi:10.1002/pmic.200600968. PMID 17570516.
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