Biology:CLDN17
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Claudin-17 is a protein that in humans is encoded by the CLDN17 gene.[1][2] It belongs to the group of claudins; claudins are cell-cell junction proteins that keep that maintains cell- and tissue-barrier function.[3] It forms anion-selective paracellular channels and is localized mainly in kidney proximal tubules.[4][5]
References
- ↑ "CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family". Int J Mol Med 11 (6): 683–9. May 2003. doi:10.3892/ijmm.11.6.683. PMID 12736707.
- ↑ "Entrez Gene: CLDN17 claudin 17". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26285.
- ↑ Adil, MS; Narayanan, SP; Somanath, PR (2021). "Cell-cell junctions: structure and regulation in physiology and pathology.". Tissue Barriers 9 (1): 1848212. doi:10.1080/21688370.2020.1848212. PMID 33300427.
- ↑ "Claudin-17 forms tight junction channels with distinct anion selectivity". Cell Mol Life Sci 69 (16): 2765–78. 2012. doi:10.1007/s00018-012-0949-x. PMID 22402829.
- ↑ Adil, M; Parvathagiri, V; Verma, A; Liu, F; Rudraraju, M; Narayanan, SP; Somanath, PR (2022). "Claudin-17 Deficiency in Mice Results in Kidney Injury Due to Electrolyte Imbalance and Oxidative Stress". Cells 11 (11): 1782. doi:10.3390/cells11111782. PMID 35681477.
External links
- Human CLDN17 genome location and CLDN17 gene details page in the UCSC Genome Browser.
Further reading
- "Tight junction proteins.". Prog. Biophys. Mol. Biol. 81 (1): 1–44. 2003. doi:10.1016/S0079-6107(02)00037-8. PMID 12475568.
- "Claudin-based barrier in simple and stratified cellular sheets.". Curr. Opin. Cell Biol. 14 (5): 531–6. 2003. doi:10.1016/S0955-0674(02)00362-9. PMID 12231346.
- "Multifunctional strands in tight junctions.". Nat. Rev. Mol. Cell Biol. 2 (4): 285–93. 2001. doi:10.1038/35067088. PMID 11283726.
- "The roles of claudin superfamily proteins in paracellular transport.". Traffic 2 (2): 93–8. 2001. doi:10.1034/j.1600-0854.2001.020203.x. PMID 11247307.
- "Tight junctions of the blood–brain barrier.". Cell. Mol. Neurobiol. 20 (1): 57–76. 2000. doi:10.1023/A:1006995910836. PMID 10690502.
- "Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins.". BMC Genomics 7: 155. 2006. doi:10.1186/1471-2164-7-155. PMID 16780588.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. 2003. doi:10.1101/gr.1293003. PMID 12975309.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Organization and formation of the tight junction system in human epidermis and cultured keratinocytes.". Eur. J. Cell Biol. 81 (5): 253–63. 2003. doi:10.1078/0171-9335-00244. PMID 12067061.
- "The DNA sequence of human chromosome 21.". Nature 405 (6784): 311–9. 2000. doi:10.1038/35012518. PMID 10830953. Bibcode: 2000Natur.405..311H.
- "A systems proteomics view of the endogenous human claudin protein family". J Proteome Res 15 (2): 339–359. 2015. doi:10.1021/acs.jproteome.5b00769. PMID 26680015. PMC 4777318. https://archive-ouverte.unige.ch/unige:79118/ATTACHMENT01.
 | This article needs additional or more specific categories. (October 2022) |
 |  |
