Biology:Calcium channel associated transcriptional regulator
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Short description: Transcription factor found in mammalian cells
Calcium channel associated transcriptional regulator (CCAT) is a transcription factor found in mammalian cells.
Generation
In neuronal cells, CCAT is generated upon activation of a cryptic promoter in exon 46 of CACNA1C, the gene that encodes the voltage-gated calcium channel Cav1.2.[1]
References
- ↑ Gomez-Ospina, Natalia; Panagiotakos, Georgia; Portmann, Thomas; Pasca, Sergiu P.; Rabah, Dania; Budzillo, Agata; Kinet, Jean Pierre; Dolmetsch, Ricardo E. (16 April 2013). "A Promoter in the Coding Region of the Calcium Channel Gene CACNA1C Generates the Transcription Factor CCAT" (in en). PLOS ONE 8 (4): e60526. doi:10.1371/journal.pone.0060526. ISSN 1932-6203. PMID 23613729. Bibcode: 2013PLoSO...860526G.
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