Biology:China Kadoorie Biobank
The China Kadoorie Biobank is acquiring genomic data on half a million Chinese participants. In 2022 Genome-wide genotyping had been conducted for more than 100,000 participants using custom-designed Axiom® arrays. [1] It collected questionnaire and physical data and blood samples on 510,000 men and women aged between 30 and 79 from 10 regions in China between 2004-2008 with the aim of investigating chronic diseases (e.g. heart attack, stroke, diabetes, and cancer). Participants have been linked to mortality registers and nationwide health systems and a sub-group of 25,000 are retested every few years. It is a joint venture by the University of Oxford’s Clinical Trial Service Unit & Epidemiological Studies Unit and the Chinese Academy of Medical Sciences. [2]
Research based on the biobank published by the American Thoracic Society in 2018 found that respiratory disease hospitalization or death were 36% higher among people who used wood or coal for cooking compared to those who used electricity or gas.[3]
A study published in Heart based on the biobank found that people who ate an egg a day had a lower incidence of cardiovascular disease overall than those who ate no eggs. They had a 25% lower incidence of hemorrhagic stroke, and a 12% reduction in risk of ischemic heart disease.[4]
A study published in 2022 examined the relative risk of mortality associated with five individual and combined lifestyle factors - never smoking or quitting not for illness, no excessive alcohol use, being physically active, healthy eating habits, and healthy body shape - and established that they could be associated with substantial gains in life expectancy in the Chinese population.[5]
References
- ↑ Walters, Robin G.; Millwood, Iona Y.; Lin, Kuang; Valle, Dan Schmidt; McDonnell, Pandora; Hacker, Alex; Avery, Daniel; Cai, Na et al. (3 May 2022). "Genotyping and population structure of the China Kadoorie Biobank". Medrxiv. doi:10.1101/2022.05.02.22274487. https://www.medrxiv.org/content/10.1101/2022.05.02.22274487v1.
- ↑ (2014) China Kadoorie Biobank University of Oxford, Retrieved 28 January 2015
- ↑ "Cooking with wood or coal is linked to increased risk of respiratory illness and death". Science Daily. 21 September 2018. https://www.sciencedaily.com/releases/2018/09/180921092447.htm. Retrieved 1 October 2018.
- ↑ "Recent studies show the benefits of eating eggs". Daily Herald. 25 August 2018. https://www.dailyherald.com/entlife/20180825/recent-studies-show-the-benefits-of-eating-eggs. Retrieved 1 October 2018.
- ↑ "Healthy lifestyle and life expectancy at age 30 years in the Chinese population: an observational study". Lancet Public Health. 1 August 2022. https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(22)00110-4/fulltext. Retrieved 11 November 2022.
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