Biology:DHRS7
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Dehydrogenase/reductase (SDR family) member 7 is a protein that in humans is encoded by the DHRS7 gene.[1]
Function
Short-chain dehydrogenases/reductases (SDRs), such as DHRS7, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids.[2][3]
References
- ↑ "Entrez Gene: Dehydrogenase/reductase (SDR family) member 7". https://www.ncbi.nlm.nih.gov/gene/51635.
- ↑ "DHRS7 (SDR34C1) – A new player in the regulation of androgen receptor function by inactivation of 5α-dihydrotestosterone?". The Journal of Steroid Biochemistry and Molecular Biology 171: 288–295. July 2017. doi:10.1016/j.jsbmb.2017.04.013. PMID 28457967.
- ↑ "Human DHRS7, promising enzyme in metabolism of steroids and retinoids?". Journal of Steroid Biochemistry and Molecular Biology 155, Part A (Pt A): 112–119. January 2016. doi:10.1016/j.jsbmb.2015.09.041. PMID 26466768.
Further reading
- "The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative". Chemico-Biological Interactions 178 (1–3): 94–8. March 2009. doi:10.1016/j.cbi.2008.10.040. PMID 19027726.
- "A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order". The Journal of Allergy and Clinical Immunology 128 (5): 996–1005. November 2011. doi:10.1016/j.jaci.2011.08.030. PMID 22036096.
- "Biochemical properties of human dehydrogenase/reductase (SDR family) member 7". Chemico-Biological Interactions 207 (1): 52–7. January 2014. doi:10.1016/j.cbi.2013.11.003. PMID 24246706.
- "Purification and reconstitution of human membrane-bound DHRS7 (SDR34C1) from Sf9 cells". Protein Expression and Purification 95: 44–49. March 2014. doi:10.1016/j.pep.2013.11.013. PMID 24316191.
- "A role for the dehydrogenase DHRS7 (SDR34C1) in prostate cancer". Cancer Medicine 4 (11): 1717–1729. November 2015. doi:10.1002/cam4.517. PMID 26311046.
- "The identification of new substrates of human DHRS7 by molecular modeling and in vitro testing". International Journal of Biological Macromolecules 105, Part 1 (Pt 1): 171–182. December 2017. doi:10.1016/j.ijbiomac.2017.07.012. PMID 28687384.
- "The Potential Tumor-Suppressor DHRS7 Inversely Correlates with EGFR Expression in Prostate Cancer Cells and Tumor Samples". Cancers (Basel) 14 (13): 3074. June 2022. doi:10.3390/cancers14133074. PMID 35804847.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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