Biology:Dactylosporangium aurantiacum
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Short description: Species of bacterium
| Dactylosporangium aurantiacum | |
|---|---|
| Scientific classification | |
| Kingdom: | |
| Phylum: | |
| Class: | Actinobacteria
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| Order: | Micromonosporales
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| Family: | |
| Genus: | |
| Species: | D. aurantiacum
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| Binomial name | |
| Dactylosporangium aurantiacum | |
Dactylosporangium aurantiacum (Thiemann et al. 1967) is a Gram-positive soil-based actinobacterium in the order Actinomycetales.[1] Like all Dactylosporangium species, aurantiacum is aerobic and mesophilic.[2]
One subspecies, hamdenesis, produces a number of 18-membered macrolide antibiotics called tiacumicins as a byproduct of fermentation.[3] One of these, tiacumicin B, commonly known as fidaxomicin,[4] has narrow-spectrum bacteriocidal action against Gram-positive anaerobic bacteria, including Clostridium difficile.
References
- ↑ "BacDive database". https://bacdive.dsmz.de/strain/7869.
- ↑ Bergey's Manual of Systematic Bacteriology: Volume 5: The Actinobacteria.
- ↑ Hochlowski, J. E.; Swanson, S. J.; Ranfranz, L. M.; Whittern, D. N.; Buko, A. M.; McAlpine, J. B. (1987). "Tiacumicins, a novel complex of 18-membered macrolides. II. Isolation and structure determination". The Journal of Antibiotics 40 (5): 575–88. doi:10.7164/antibiotics.40.575. PMID 3610816.
- ↑ Baktash, A.; Terveer, E. M.; Zwittink, R. D.; Hornung, B. V.; Corver, J.; Kuijper, E. J.; Smits, W. K. (2018). "Mechanistic Insights in the Success of Fecal Microbiota Transplants for the Treatment of Clostridium difficile Infections". Frontiers in Microbiology 9: 1242. doi:10.3389/fmicb.2018.01242. PMID 29946308.
Wikidata ☰ Q25841624 entry
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