Biology:Dopachrome tautomerase
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Generic protein structure example |
See also
- Tyrosinase-related protein 1 (TYRP1)
- Dopachrome, a cyclization product of L-DOPA and is an intermediate in the biosynthesis of melanin.
References
- ↑ "Entrez Gene: DCT dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1638.
- ↑ "Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling". EMBO J. 21 (11): 2703–14. 2002. doi:10.1093/emboj/21.11.2703. PMID 12032083.
- ↑ "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. 2008. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971.
Further reading
- "A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus". EMBO J. 11 (2): 527–35. 1992. doi:10.1002/j.1460-2075.1992.tb05083.x. PMID 1537334.
- "The presence of tyrosinase and related proteins in human epidermis and their relationship to melanin type". Pigment Cell Res. 7 (4): 204–9. 1995. doi:10.1111/j.1600-0749.1994.tb00050.x. PMID 7855064.
- "Levels of dopachrome tautomerase in human melanocytes cultured in vitro". Melanoma Res. 4 (5): 287–91. 1995. doi:10.1097/00008390-199410000-00003. PMID 7858411.
- "Cloning of the human DOPAchrome tautomerase/tyrosinase-related protein 2 gene and identification of two regulatory regions required for its pigment cell-specific expression". J. Biol. Chem. 269 (43): 27080–7. 1994. doi:10.1016/S0021-9258(18)47128-1. PMID 7929451.
- "High-molecular-weight forms of tyrosinase and the tyrosinase-related proteins: evidence for a melanogenic complex". J. Invest. Dermatol. 103 (2): 196–201. 1994. doi:10.1111/1523-1747.ep12392743. PMID 8040609.
- "Assignment of the tyrosinase-related protein-2 gene (TYRP2) to human chromosome 13q31-q32 by fluorescence in situ hybridization: extended synteny with mouse chromosome 14". Genomics 21 (1): 293–6. 1994. doi:10.1006/geno.1994.1266. PMID 8088811.
- "Contribution of melanogenic proteins to the heterogeneous pigmentation of human melanocytes". J. Cell Sci. 106 (4): 1323–31. 1994. doi:10.1242/jcs.106.4.1323. PMID 8126111.
- "Molecular cloning and functional analysis of a cDNA coding for human DOPAchrome tautomerase/tyrosinase-related protein-2". Biochim. Biophys. Acta 1217 (3): 317–21. 1994. doi:10.1016/0167-4781(94)90292-5. PMID 8148378.
- "Sequence of the human dopachrome tautomerase-encoding TRP-2 cDNA". Gene 143 (2): 295–8. 1994. doi:10.1016/0378-1119(94)90114-7. PMID 8206391.
- "Isolation of a new tautomerase monitored by the conversion of D-dopachrome to 5,6-dihydroxyindole". Biochem. Biophys. Res. Commun. 197 (2): 619–24. 1994. doi:10.1006/bbrc.1993.2524. PMID 8267597.
- "Molecular characterization of a human tyrosinase-related-protein-2 cDNA. Patterns of expression in melanocytic cells". Eur. J. Biochem. 219 (1–2): 127–34. 1994. doi:10.1111/j.1432-1033.1994.tb19922.x. PMID 8306979.
- "Chromosomal structure of the human TYRP1 and TYRP2 loci and comparison of the tyrosinase-related protein gene family". Genomics 29 (1): 24–34. 1996. doi:10.1006/geno.1995.1211. PMID 8530077.
- "A new enzyme activity in human blood cells and isolation of the responsible protein (D-dopachrome tautomerase) from erythrocytes". Eur. J. Haematol. 57 (3): 254–6. 1996. doi:10.1111/j.1600-0609.1996.tb01372.x. PMID 8898931.
- "Human ocular melanocytes and retinal pigment epithelial cells differ in their melanogenic properties in vivo and in vitro". Curr. Eye Res. 15 (11): 1079–91. 1997. doi:10.3109/02713689608995139. PMID 8950502.
- "Identification of TRP-2 as a Human Tumor Antigen Recognized by Cytotoxic T Lymphocytes". J. Exp. Med. 184 (6): 2207–16. 1997. doi:10.1084/jem.184.6.2207. PMID 8976176.
- "Molecular detection of tumor-associated antigens shared by human cutaneous melanomas and gliomas". Am. J. Pathol. 150 (6): 2143–52. 1997. PMID 9176405.
- "Crystallization and preliminary X-ray analysis of human D-dopachrome tautomerase". J. Struct. Biol. 120 (1): 105–8. 1997. doi:10.1006/jsbi.1997.3904. PMID 9356298.
- "Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation". Biochem. Biophys. Res. Commun. 243 (2): 538–44. 1998. doi:10.1006/bbrc.1998.8123. PMID 9480844.
- "Quantification of tyrosinase, TRP-1, and Trp-2 transcripts in human melanocytes by reverse transcriptase-competitive multiplex PCR--regulation by steroid hormones". J. Invest. Dermatol. 110 (4): 364–7. 1998. doi:10.1046/j.1523-1747.1998.00144.x. PMID 9540976.
- "Translation of a Retained Intron in Tyrosinase-related Protein (TRP) 2 mRNA Generates a New Cytotoxic T Lymphocyte (CTL)-defined and Shared Human Melanoma Antigen Not Expressed in Normal Cells of the Melanocytic Lineage". J. Exp. Med. 188 (6): 1005–16. 1998. doi:10.1084/jem.188.6.1005. PMID 9743519.