Biology:EPR1

Short description: Human gene

Generic protein structure example

Effector cell peptidase receptor 1, also known as EPR1, is a human gene.

This locus represents an antisense transcript of the survivin locus. This record was withdrawn in collaboration with HGNC. It was defined by L26245.1, which appears to be a cloning artifact ("The elusive factor Xa receptor: failure to detect transcripts that correspond to the published sequence of EPR-1". Blood 96 (1): 145–8. July 2000. doi:10.1182/blood.v96.1.145. PMID 10891443. ).(This information come from https://www.ncbi.nlm.nih.gov/gene?term=L26245.1)

Further reading

• Altieri DC (1995). "Xa receptor EPR-1". FASEB J. 9 (10): 860–5. doi:10.1096/fasebj.9.10.7615156. PMID 7615156. 
• Altieri DC (1994). "Splicing of effector cell protease receptor-1 mRNA is modulated by an unusual retained intron". Biochemistry 33 (46): 13848–55. doi:10.1021/bi00250a039. PMID 7947793. 
• Altieri DC (1994). "Molecular cloning of effector cell protease receptor-1, a novel cell surface receptor for the protease factor Xa". J. Biol. Chem. 269 (5): 3139–42. doi:10.1016/S0021-9258(17)41838-2. PMID 8106347. 
• "Activation-dependent exposure of the inter-EGF sequence Leu83-Leu88 in factor Xa mediates ligand binding to effector cell protease receptor-1". J. Biol. Chem. 272 (13): 8340–5. 1997. doi:10.1074/jbc.272.13.8340. PMID 9079657. 
• "Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting". J. Biol. Chem. 273 (18): 11177–82. 1998. doi:10.1074/jbc.273.18.11177. PMID 9556606. 
• "The elusive factor Xa receptor: failure to detect transcripts that correspond to the published sequence of EPR-1". Blood 96 (1): 145–8. 2000. doi:10.1182/blood.v96.1.145. PMID 10891443. 
• "On the role of EPR-1 or an EPR-1-like molecule in regulating factor Xa incorporation into platelet prothrombinase". Thromb. Haemost. 86 (4): 1133–5. 2002. doi:10.1055/s-0037-1616557. PMID 11686347. 
• "Downregulation of survivin expression by induction of the effector cell protease receptor-1 reduces tumor growth potential and results in an increased sensitivity to anticancer agents in human colon cancer". Eur. J. Cancer 38 (17): 2316–24. 2003. doi:10.1016/S0959-8049(02)00247-2. PMID 12441269. 
• "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
• "Significance of effector protease receptor-1 expression and its relationship with proliferation and apoptotic index in patients with primary advanced gastric adenocarcinoma". World J. Gastroenterol. 10 (9): 1262–7. 2004. doi:10.3748/wjg.v10.i9.1262. PMID 15112339. 
• "Transcriptome analysis of human gastric cancer". Mamm. Genome 16 (12): 942–54. 2006. doi:10.1007/s00335-005-0075-2. PMID 16341674.