Biology:Glypican 5
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 Generic protein structure example |
Glypican-5 is a protein that in humans is encoded by the GPC5 gene.[1][2]
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.[2]
See also
- Glypican
References
- ↑ "Characterization of glypican-5 and chromosomal localization of human GPC5, a new member of the glypican gene family". Genomics 40 (1): 24–30. Jun 1997. doi:10.1006/geno.1996.4518. PMID 9070915.
- ↑ 2.0 2.1 "Entrez Gene: GPC5 glypican 5". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2262.
Further reading
- "Developmental roles of the glypicans.". Semin. Cell Dev. Biol. 12 (2): 117–25. 2001. doi:10.1006/scdb.2000.0240. PMID 11292377.
- "K-glypican: a novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney.". J. Cell Biol. 130 (5): 1207–18. 1995. doi:10.1083/jcb.130.5.1207. PMID 7657705.
- "Expression of the cell surface proteoglycan glypican-5 is developmentally regulated in kidney, limb, and brain.". Dev. Biol. 190 (1): 78–93. 1997. doi:10.1006/dbio.1997.8690. PMID 9331333. https://escholarship.org/content/qt3td2w2cq/qt3td2w2cq.pdf?t=oyqmc1.
- "A 4-Mb BAC/PAC contig and complete genomic structure of the GPC5/GPC6 gene cluster on chromosome 13q32.". Matrix Biol. 20 (5–6): 375–85. 2002. doi:10.1016/S0945-053X(01)00143-3. PMID 11566272.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "GPC5 is a possible target for the 13q31-q32 amplification detected in lymphoma cell lines". J. Hum. Genet. 48 (6): 331–5. 2004. doi:10.1007/s10038-003-0026-2. PMID 12721791.
- "The DNA sequence and analysis of human chromosome 13". Nature 428 (6982): 522–8. 2004. doi:10.1038/nature02379. PMID 15057823. Bibcode: 2004Natur.428..522D.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
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