Biology:Hepatitis C virus envelope glycoprotein E2

From HandWiki
HCV genome

E2 is a viral structural protein found in the hepatitis C virus.[1][2] It is present on the viral envelope and functions as a host receptor binding protein, mediating entry into host cells. It is a key target for the design of entry inhibitors and vaccine immunogens.[3]

References

  1. ↑ "Hepatitis C virus (HCV) E1 and E2 protein regions that specifically bind to HepG2 cells". Journal of Hepatology 36 (2): 254–62. 2002. doi:10.1016/S0168-8278(01)00262-8. PMID 11830338. 
  2. ↑ "Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes". The Journal of Experimental Medicine 197 (5): 633–42. 2003. doi:10.1084/jem.20021756. PMID 12615904. PMC 2193821. http://www.hal.inserm.fr/inserm-00133783/document. 
  3. ↑ "Hepatitis C virus E2 envelope glycoprotein core structure". Science 342 (6162): 1090–4. 2013. doi:10.1126/science.1243876. PMID 24288331. Bibcode: 2013Sci...342.1090K. 




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