Biology:Hya RNA motif
From HandWiki
hya | |
---|---|
Consensus secondary structure and sequence conservation of hya RNA | |
Identifiers | |
Symbol | hya |
Rfam | RF02992 |
Other data | |
RNA type | Cis-reg |
SO | 0005836 |
PDB structures | PDBe |
The hya RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] hya motif RNAs are found in Actinomycetota.
hya motif RNAs likely function as cis-regulatory elements, in view of their positions upstream of protein-coding genes. Indeed, the RNAs are upstream of multiple genes that encode non-homologous proteins. If all examples of the RNA were upstream of homologous genes, there is the possibility that the RNAs were conserved in that position simply by inheritance. The non-homology of the genes downstream of hya RNAs makes this scenario less likely. The genes presumably regulated by hya RNAs are subunits of nickel-iron hydrogenase I.
References
- ↑ "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. October 2017. doi:10.1093/nar/gkx699. PMID 28977401.
Original source: https://en.wikipedia.org/wiki/Hya RNA motif.
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