Biology:Int-alpA RNA motif

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int-alpA
RF02996.svg
Consensus secondary structure and sequence conservation of int-alpA RNA
Identifiers
Symbolint-alpA
RfamRF02996
Other data
RNA typeGene; sRNA
SO0001263
PDB structuresPDBe

The int-alpA RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] int-alpA motif RNAs are found in Pseudomonadota, and one example is known in each of Acidobacteriota and Planctomycetota. An int-alpA was also detected in a purified phage, specifically Thalssomonas phage BA3.

int-alpA RNAs likely function in trans as small RNAs. They are often located nearby to integrase genes that most resemble the homologous gene found in the P4 phage. int-alpA RNAs also often occur nearby to alpA genes, a gene that is also related to phages. Thus the RNA motif seems to function as part of phages.

References