Biology:Intracellular

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In cell biology, molecular biology and related fields, the word intracellular means "inside the cell".[1]

It is used in contrast to extracellular (outside the cell). The cell membrane (and, in many organisms, the cell wall) is the barrier between the two, and chemical composition of intra- and extracellular milieu (Milieu intérieur) can be radically different. In most organisms, for example, a Na+/K+ ATPase maintains a high potassium level inside cells while keeping sodium low, leading to chemical excitability.[2][3]

A commonly used notation is [math]\displaystyle{ [S]_i }[/math] to denote the intracellular concentration of a substrate [math]\displaystyle{ S }[/math]. For example, [math]\displaystyle{ [Ca^{2+}]_i }[/math] is the intracellular concentration of Calcium.

See also

References

  1. "Definition of Intracellular". http://www.medterms.com/script/main/art.asp?articlekey=24383. 
  2. Matsudaira, Paul T.; Lodish, Harvey F.; Arnold Berk; Kaiser, Chris; Monty Krieger; Matthew P Scott; Anthony Bretscher; Hidde Ploegh (2008). Molecular cell biology. San Francisco: W.H. Freeman. ISBN 0-7167-7601-4. 
  3. "Novel p-type ATPases mediate high-affinity potassium or sodium uptake in fungi". Eukaryotic Cell 3 (2): 359–68. April 2004. doi:10.1128/ec.3.2.359-368.2004. PMID 15075266. PMC 387655. http://pubman.mpdl.mpg.de/pubman/item/escidoc:1222291/component/escidoc:1222290/benito_schreier_eukaryotic_cell_2004.pdf. 

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