Biology:M23 RNA motif
| M23 | |
|---|---|
 Consensus secondary structure and sequence conservation of M23 RNA | |
| Identifiers | |
| Symbol | M23 |
| Rfam | RF03006 |
| Other data | |
| RNA type | Gene; sRNA |
| SO | 0001263 |
| PDB structures | PDBe |
The M23 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] M23 motif RNAs are found in Clostridia.
M23 RNAs are generally located upstream of protein-coding genes, and therefore they might function as cis-regulatory elements. Most M23 RNAs are located upstream of M23 peptidase genes, but one is upstream of a gene whose product is NAD synthetase. However, there were two cases where no downstream gene was located.[1] While these cases had technical explanations not related to biology,[1] it is possible they the technical explanations do not apply, and that the M23 RNA motif functions as a small RNA.
An M23 RNA was observed to apparently bind a molecule in yeast extract.[1] However, this putative molecule has not (as of 2018) been identified.
References
- ↑ 1.0 1.1 1.2 1.3 "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Research 45 (18): 10811–10823. October 2017. doi:10.1093/nar/gkx699. PMID 28977401.
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